1344028-77-8Relevant articles and documents
Halogen substituents on the aromatic moiety of the tetracaine scaffold improve potency of cyclic nucleotide-gated channel block
Kirk, Sarah R.,Jackson, Evan P.,Cuellar, Elysia,Andrade, Adriana L.,Melich, Kenneth,Karpen, Jeffrey W.
, p. 6417 - 6419 (2011)
A series of new tetracaine derivatives with substituents on the aromatic ring was prepared and evaluated for block of retinal rod cyclic nucleotide-gated (CNG) channels. Aromatic substitutions had little effect starting with the basic tetracaine scaffold,