1344663-93-9

Basic information

• Product Name: 6-chloro-3-nitro-2-phenylpyridine-1-oxide
• Synonyms: 6-chloro-3-nitro-2-phenylpyridine-1-oxide
• CAS NO: 1344663-93-9
• Molecular Weight: 250.641
• Mol File: 1344663-93-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-3-nitro-2-phenylpyridine-1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-3-nitro-2-phenylpyridine-1-oxide(1344663-93-9)
• EPA Substance Registry System: 6-chloro-3-nitro-2-phenylpyridine-1-oxide(1344663-93-9)

Safety Data

• Hazardous Substances Data: 1344663-93-9(Hazardous Substances Data)

Upstream product

• 13198-73-7 2-Chloro-5-nitropyridine-1-oxide 
• 100-58-3 phenylmagnesium bromide 

Relevant articles and documents

Facile one-pot direct arylation and alkylation of nitropyridine N -oxides with grignard reagents

Facile arylation and alkylation of nitropyridine N-oxides were developed through the reactions of Grignard reagents with nitropyridine N-oxides. For the same 4-nitropyridine N-oxide, arylation occurred at the 2- (or 6-) position, whereas alkylation occurred at the 3-position in an adjustably site-selective manner. The cooperative action of the two groups was discovered in the reactions of 3-nitropyridine N-oxides. This protocol can find wide applications in building various pyridine compounds as illustrated in total syntheses of Emoxipin and Caerulomycin A and E.