134863-85-7

Basic information

• Product Name: Cyclohexaneacetonitrile, a-[(trimethylsilyl)oxy]-, (R)-
• CAS NO: 134863-85-7
• Molecular Formula: C11H21NOSi
• Molecular Weight: 211.379
• Mol File: 134863-85-7.mol
• Article Data: 62

Chemical Properties

• CAS DataBase Reference: Cyclohexaneacetonitrile, a-[(trimethylsilyl)oxy]-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexaneacetonitrile, a-[(trimethylsilyl)oxy]-, (R)-(134863-85-7)
• EPA Substance Registry System: Cyclohexaneacetonitrile, a-[(trimethylsilyl)oxy]-, (R)-(134863-85-7)

Safety Data

• Hazardous Substances Data: 134863-85-7(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 2043-61-0 cyclohexanecarbaldehyde 
• 7677-24-9 trimethylsilyl cyanide 
• 4354-47-6 (R)-2-cyclohexyl-2-hydroxyacetonitrile 
• 151-50-8 potassium cyanide 
• 2408-36-8 lithium cyanide 

Downstream Products

• 100007-62-3 2-cyclohexyl-2-hydroxyacetonitrile 
• 36677-67-5 2-cyclohexyl-2-hydroxy-1-phenylethan-1-one 
• 4354-47-6 (R)-2-cyclohexyl-2-hydroxyacetonitrile 
• 4354-47-6 (S)-2-cyclohexyl-2-hydroxyacetonitrile 
• 1379452-55-7 (R)-2-cyclohexyl-2-phenylacetonitrile 
• 6006-68-4 (+/-)-1-cyclohexyl-2-phenylethanol 
• 88522-70-7 1-Cyclohexyl-1-hydroxy-tetradecan-2-one 

Relevant articles and documents

A ketone-functionalized Zn-MOF for solvent-free cyanosilylation of aldehyde and treatment activity against osteosarcoma trough increasing Mg63 cells autophagy

In this work, 5,5′-carbonyldiisophthalic acid (H4cipa) was used as a ligand to react with Zn(NO3)2·6H2O in a mixed solvent of DMF and water to prepare a new metal-organic framework (MOF) with the chemical formul

A Stable Porphyrin-Based Porous mog Metal-Organic Framework as an Efficient Solvent-Free Catalyst for C-C Bond Formation

We herein report the porous 4-fold interpenetrated mog (moganite) metal-organic framework (MOF) [Cd3(tipp)(bpdc)2]·DMA·9H2O (1·Cd; H2tipp = 5,10,15,20-tetrakis(4-(imidazol-1-yl)phenyl)porphyrin, H2bpd

Germyliumylidene: A Versatile Low Valent Group 14 Catalyst

Bis-NHC stabilized germyliumylidenes [RGe(NHC)2]+ are typically Lewis basic (LB) in nature, owing to their lone pair and coordination of two NHCs to the vacant p-orbitals of the germanium center. However, they can also show Lewis acidity (LA) via Ge?CNHC σ* orbital. Utilizing this unique electronic feature, we report the first example of bis-NHC-stabilized germyliumylidene [MesTerGe(NHC)2]Cl (1), (MesTer=2,6-(2,4,6-Me3C6H2)2C6H3; NHC= IMe4=1,3,4,5-tetramethylimidazol-2-ylidene) catalyzed reduction of CO2 with amines and arylsilane, which proceeds via its Lewis basic nature. In contrast, the Lewis acid nature of 1 is utilized in the catalyzed hydroboration and cyanosilylation of carbonyls, thus highlighting the versatile ambiphilic nature of bis-NHC stabilized germyliumylidenes.

The direct trifluoromethylsilylation and cyanosilylation of aldehydes: via an electrochemically induced intramolecular pathway

The initiator-free electrochemical trifluoromethylsilylation and cyanosilylation of aldehydes were developed in an undivided cell. A DFT study reveals that the direct cathodic activation of trimethylsilyl reagents significantly released the congestion around the 'Si' atom, allowing the Si-O bond affinity to form concerted anion intermediates with aldehydes. Thus, intramolecular -CF3 and -CN migration make the reactions much easier to carry out without initiators.