1352242-48-8

Basic information

• Product Name: 2-methyl-N₁-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine
• Synonyms: 2-methyl-N₁-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine
• CAS NO: 1352242-48-8
• Molecular Weight: 277.329
• Mol File: 1352242-48-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-methyl-N₁-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-N₁-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine(1352242-48-8)
• EPA Substance Registry System: 2-methyl-N₁-(4-(pyridin-3-yl)pyrimidin-2-yl)benzene-1,3-diamine(1352242-48-8)

Safety Data

• Hazardous Substances Data: 1352242-48-8(Hazardous Substances Data)

Upstream product

• 796738-71-1 N-(2-methyl-4-nitrophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine 
• 483324-01-2 2-chloro-4-(pyridin-3-yl)pyrimidine 

Downstream Products

• 1207534-73-3 N-[2-methyl-3-(4-pyridin-3-ylpyrimidin-2-ylamino)phenyl]-3,5-dinitrobenzamide 

Relevant articles and documents

SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES

This application discloses compounds according to generic Formula (I): wherein all variables are defined as described herein which exhibit strong inhibition effects on various cancer cell lines. The compounds disclosed herein are useful for the treatment of proliferative diseases, including neoplastic diseases such as cancer and non- neoplastic disorders such as rheumatoid arthritis. Also disclosed are pharmaceutical compositions containing compounds of Formula (I) and at least one carrier, diluent or excipient and optionally one or more additional therapeutically active agents, including anticancer agents. This application also discloses methods for treating a proliferative disease, including neoplastic diseases such as cancer and non- neoplastic disorders such as rheumatoid arthritis.