13531-52-7

Basic information

• Product Name: N-(2-AMINOETHYL)-1,3-PROPANEDIAMINE
• Synonyms: 3-(2-AMINOETHYLAMINO)PROPYLAMINE;3-Propanediamine,N-(2-aminoethyl)-1;n-(2-aminoethyl)-3-propanediamine;N-(3-Aminopropyl)ethylenediamine;N3-AMINE;N-(2-AMINOETHYL)TRIMETHYLENE DIAMINE;N-(2-AMINOETHYL)-1,3-PROPANEDIAMINE;N1-(2-AMINOETHYL)PROPANE-1,3-DIAMINE
• CAS NO: 13531-52-7
• Molecular Formula: C₅H₁₅N₃
• Molecular Weight: 117.19
• EINECS: 236-882-0
• Product Categories: Nitrogen Compounds;Organic Building Blocks;Polyamines
• Mol File: 13531-52-7.mol
• Article Data: 10

Chemical Properties

• Melting Point: 10 °C
• Boiling Point: 221 °C
• Flash Point: 205 °F
• Appearance: clear liquid
• Density: 0.928 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.126mmHg at 25°C
• Refractive Index: n20/D 1.4815(lit.)
• Storage Temp.: Store below +30°C.
• PKA: 10.17±0.10(Predicted)
• Explosive Limit: 1.0-8.1%(V)
• CAS DataBase Reference: N-(2-AMINOETHYL)-1,3-PROPANEDIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-AMINOETHYL)-1,3-PROPANEDIAMINE(13531-52-7)
• EPA Substance Registry System: N-(2-AMINOETHYL)-1,3-PROPANEDIAMINE(13531-52-7)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-28-36/37/39-45
• RIDADR: UN 2735 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 13531-52-7(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR LIQUID

Uses

N-(2-Aminoethyl)-1,3-propanediamine has been used as a templating agent in the synthesis of a new open framework iron(III) phosphite {(C5H18N3)[Fe3(HPO3)6].3H2O}. It has also been used in the preparation of dinitrocobalt(III) compound: (11-amino-4-methyl-5,8-diazaundeca-2,4-dien-2-olato-kappa4N(5,8,11),O)-dinitrocobalt(III), [Co(C10H20N3O)(NO2)2].

Flammability and Explosibility

Nonflammable

InChI:InChI=1/C5H15N3/c6-2-1-4-8-5-3-7/h8H,1-7H2/p+3

Upstream product

• 151-56-4 ethyleneimine 
• 109-76-2 Trimethylenediamine 
• 107-15-3 ethylenediamine 
• 107-13-1 acrylonitrile 
• 3217-00-3 N,N'-bis-(2-cyanoethyl)ethylenediamine 
• 56576-72-8 N,N,N'-tris(2-cyanoethyl)-1,2-ethylenediamine 
• 22584-31-2 N-(β-cyanoethyl)ethylenediamine 
• 14753-26-5 3-chloropropan-1-amine 
• 503-29-7 azetidine 

Downstream Products

• 128750-19-6 N-2-Phenylethyl-N'-<2-(2-phenylethylamino)-ethyl>-propan-1,3-diamin-trihydrochlorid 
• 128750-20-9 N-3-Phenylpropyl-N'-<2-(3-phenylpropylamino)-ethyl>-propan-1,3-diamin-trihydrochlorid 
• 216772-98-4 N,N'-bis(1-hydroxy-2-benzyliden) 1,6-diamino-3-azahexane 
• 1416971-82-8 2-(4-hydroxy-3-methoxyphenyl)-N-(3-(2-(2-(4-hydroxy-3-methoxyphenyl)acetamido)ethylamino)propyl)acetamide trifluoroacetic acid salt 
• 1416971-86-2 2-(3,4-dihydroxyphenyl)-N-(3-(2-(2-(3,4-dihydroxyphenyl)acetamido)ethylamino)propyl)acetamide trifluoroacetic acid salt 
• 142038-97-9 N₁-(3-(benzyloxycarbonylamino)propyl)-1,2-diaminoethane 
• 221296-50-0 tert-butyl 2-(3-aminopropylamino)ethylcarbamate 
• 161693-95-4 8-benzyl-1,4,12-tritosyl-1,4,8,12-tetraazacyclopentadecane 
• 161693-97-6 8-benzyl-1,4,12-tri-Boc-1,4,8,12-tetraazacyclopentadecane 
• 161693-96-5 8-benzyl-1,4,8,12-tetraazacyclopentadecane 

Relevant articles and documents

Synthesis of aminoethyl derivatives of alpha, omega-alkylenediamines and structure-activity relationships for the polyamine-bovine plasma amine oxidase system.

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TRANSAMINATION OF NITROGEN-CONTAINING COMPOUNDS TO MAKE CYCLIC AND CYCLIC/ACYCLIC POLYAMINE MIXTURES

A transamination process is described to prepare polyamine product mixtures from reactants comprising mixed nitrogen-containing compounds with binary carbon spacing between nitrogen-containing groups (a binary component). A second nitrogen-containing component with a second carbon atom spacing between nitrogen-containing groups may also be employed. The molar ratio between the binary and second components can be adjusted to customize the product composition for desired end uses.

First unequivocal synthesis of 1 or 8-N-monosubstituted 1,4,8,12-tetraazacyclopentadecane

A novel method derived from Kaden's modification of the Richman and Atkins's cyclization using tosylated synthons allows the unequivocal synthesis of 1 and 8-monofunctionalized 1,4,8,12-tetraazacyclo-pentadecane. Both syntheses are described.