1355011-60-7

Basic information

• Product Name: 4-oxo-5-phenyl-1,4-dihydropyridine-3-carboxylic acid
• Synonyms: 4-oxo-5-phenyl-1,4-dihydropyridine-3-carboxylic acid
• CAS NO: 1355011-60-7
• Molecular Weight: 215.208
• Mol File: 1355011-60-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-oxo-5-phenyl-1,4-dihydropyridine-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-5-phenyl-1,4-dihydropyridine-3-carboxylic acid(1355011-60-7)
• EPA Substance Registry System: 4-oxo-5-phenyl-1,4-dihydropyridine-3-carboxylic acid(1355011-60-7)

Safety Data

• Hazardous Substances Data: 1355011-60-7(Hazardous Substances Data)

Upstream product

• 72676-86-9 ethyl 5-phenyl-4-oxo-1,4-dihydro-3-pyridinecarboxylate 
• 718-08-1 ethyl 3-oxo-4-phenylbutyrate 
• 20320-59-6 diethyl 2-(2-phenylacetyl)malonate 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 74965-87-0 2,2-dimethyl-5-(2-phenylacetyl)-1,3-dioxane-4,6-dione 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 1474050-15-1 4-oxo-N-(2-oxoindolin-6-yl)-5-phenyl-1,4-dihydropyridine-3-carboxamide 

Relevant articles and documents

PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF

The present invention discloses a pyrido-azacyclic compound represented by formula I, an isomer thereof, a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate thereof, a preparation process thereof and a composition comprising the compound, and a use thereof as a multi-target protein kinase inhibitor in the preparation of a medicament for the treatment of diseases that are associated with protein kinase, especially c-Met, such as cancer and the like. The compound represented by formula I has potent inhibitory activity on tumor cells with overexpression of c-Met kinase, can effectively target c-Met-mediated signaling pathway, and can be used in the treatment of diseases such as cancer and the like that is caused by the overexpression of c-Met kinase.