136194-92-8

Basic information

• Product Name: ALOC-SER-OME
• Synonyms: ALLYLOXYCARBONYL-L-SERINE METHYL ESTER;ALOC-SERINE-OME;ALOC-SER-OME
• CAS NO: 136194-92-8
• Molecular Formula: C₈H₁₃NO₅
• Molecular Weight: 203.19
• Mol File: 136194-92-8.mol

Chemical Properties

• Appearance: /
• Storage Temp.: -15°C
• CAS DataBase Reference: ALOC-SER-OME(CAS DataBase Reference)
• NIST Chemistry Reference: ALOC-SER-OME(136194-92-8)
• EPA Substance Registry System: ALOC-SER-OME(136194-92-8)

Safety Data

• Hazardous Substances Data: 136194-92-8(Hazardous Substances Data)

Upstream product

• 2788-84-3 (S)-serine methyl ester 
• 1333925-60-2 (S)-2-allyloxycarbonylamino-3-allyloxycarbonyloxypropionic acid methyl ester 
• 75-33-2 2-propanethiol 

Downstream Products

• 1333925-94-2 (2S,2'S)-3,3,3-trifluoro-2-methoxy-2-phenylpropionic acid (2'-allyloxycarbonyl-2'-methoxycarbonylethyl) ester 
• 221351-11-7 N-Allyloxycarbonyl-O-(3'-O-acetyl-6-N-phenylacetyl-2'-deoxycytidine-allyl-phosphato)-L-seryl-L-glutamic acid γ-allyl ester-methoxyethyl ester 
• 221351-10-6 N-Allyloxycarbonyl-O-(3'-O-acetyl-6-N-phenylacetyl-2'-deoxycytidine-allyl-phosphato)-L-seryl-L-glutamic acid-γ-allyl ester methyl ester 
• 197727-37-0 N-Allyloxycarbonyl-O-(3'-O-acetyl-6-N-phenylacetyl-2'-deoxycytidine-allyl-phosphato)-L-seryl-L-valyl-L-phenylalanine-methoxyethoxyethyl ester 
• 197727-35-8 N-Allyloxycarbonyl-O-(3'-O-acetyl-6-N-phenylacetyl-2'-deoxycytidine-allyl-phosphato)-L-serine-L-glutamic acid γ-allyl ester-methoxyethoxyethyl ester 
• 197727-36-9 N-Allyloxycarbonyl-O-(3'-O-acetyl-6-N-phenylacetyl-2'-deoxycytidine-allyl-phosphato)-L-seryl-L-phenylalanine-methoxyethoxyethyl ester 

Relevant articles and documents

Synthesis method and application of 1-aza -5-germanium-5-alkyl bicyclic [3.3.3] undecane compound.

The invention provides a 1-aza-5-germanium hetero-5-alkyl bicyclic [3.3.3] hendecane compound having a structure shown in the formula I, and the types of the 1-aza-5-germanium hetero-5-alkyl bicyclic[3.3.3] hendecane compound are expanded. The provided compound can serve as a nucleophilic reagent, the air and humidity conditions of the nucleophilic reagent are stable, and the efficiency of the Ge-Stille coupling reaction of aryl halogen and the 1-aza-5-germanium hetero-5-alkyl bicyclic [3.3.3] hendecane compound is high.

A mild ligand-free iron-catalyzed liberation of alcohols from allylcarbonates

Different from most carbonates the allyloxy carbonyl protecting group can be cleaved under neutral conditions using metal catalysis. However, most of the catalysts employed to date are based upon precious metals. Herein we present two protocols for the mild Fe-catalyzed liberation of alcohols from allylcarbonates that are characterized by broad functional group tolerance and exclusive chemoselectivity.

Polymer-bound p-alkoxybenzyl trichloracetimidates: Reagents for the protection of alcohols as benzyl ethers on solid-phase

Wang and Tentagel resins ware converted into their trichloroacetimidate dervatives and used as polymer-bound benzylating reagents for a variety of alcohols. Loading and cleavage proceed in good to excellent yields in the presence of BF3.OEt2 and 1% TFA respectively. The resins have excellent shelf life.