13677-45-7

Basic information

• Product Name: Benzenemethanol, 4-methoxy-a-(2-phenylethenyl)-
• CAS NO: 13677-45-7
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• Mol File: 13677-45-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-methoxy-a-(2-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-methoxy-a-(2-phenylethenyl)-(13677-45-7)
• EPA Substance Registry System: Benzenemethanol, 4-methoxy-a-(2-phenylethenyl)-(13677-45-7)

Safety Data

• Hazardous Substances Data: 13677-45-7(Hazardous Substances Data)

Upstream product

• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 100-52-7 benzaldehyde 
• 5720-07-0 4-methoxyphenylboronic acid 
• 104-55-2 3-phenyl-propenal 
• 959-23-9 4'-methoxychalcone 

Downstream Products

• 959-23-9 4'-methoxychalcone 
• 184944-46-5 C₂₁H₂₂O₃ 
• 184944-45-4 C₂₁H₂₂O₃ 
• 5739-38-8 1-(4-methoxyphenyl)-3-phenylpropan-1-one 
• 93698-11-4 3-deuterio-1,3-diphenyl-1-propanone 
• 20442-73-3 (1E)-3-(4-methoxyphenyl)-1-phenylpropene 
• 35856-81-6 1-methoxy-4-[(1E)-3-phenylprop-1-en-1-yl]benzene 

Relevant articles and documents

Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol

One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.

Bi(OTf)3 catalyzed disproportionation reaction of cinnamyl alcohols

Bi(OTf)3 catalyzed disproportionation reaction of cinnamyl alcohols provides chalcones and benzyl styrenes. The use of various metal triflates is investigated herein for facile and efficient redox transformation. A plausible mechanism has been proposed.

Lithium amidoborane, a highly chemoselective reagent for the reduction of α,β-unsaturated ketones to allylic alcohols

Lithium amidoborane (LiNH2BH3, LiAB for short), is capable of chemoselectively reducing α,β-unsaturated ketones to the corresponding allylic alcohols at ambient temperature. A mechanistic study shows that the reduction is via a double hydrogen transfer process. The protic H(N) and hydridic H(B) in amidoborane add to the O and C sites of the carbonyl group, respectively.