Welcome to LookChem.com Sign In|Join Free

Cas Database

1374448-05-1

1374448-05-1

Identification

  • Product Name:N-(3,4-dichlorophenyl)-N-methyl-2-diazo-3-oxobutanamide

  • CAS Number: 1374448-05-1

  • EINECS:

  • Molecular Weight:286.117

  • Molecular Formula: C11H9Cl2N3O2

  • HS Code:

  • Mol File:1374448-05-1.mol

Synonyms:N-(3,4-dichlorophenyl)-N-methyl-2-diazo-3-oxobutanamide

Post Buying Request Now
Entrust LookChem procurement to find high-quality suppliers faster

Safety information and MSDS

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase

Relevant articles and documentsAll total 1 Articles be found

Ruthenium-catalyzed intramolecular cyclization of diazo-β-ketoanilides for the synthesis of 3-alkylideneoxindoles

Chan, Wai-Wing,Kwong, Tsz-Lung,Yu, Wing-Yiu

, p. 3749 - 3755 (2012/06/01)

With [Ru(p-cymene)Cl2]2 as catalyst, diazo-β-ketoanilides would undergo intramolecular carbenoid arene C-H bond functionalization to afford 3-alkylideneoxindoles in up to 92% yields. The reaction occurs under mild conditions and exhibits excellent chemoselectivity. The lack of primary KIE (kH/kD ~ 1) suggests that the reaction should not proceed by rate-limiting C-H bond cleavage; a mechanism involving cyclopropanation of the arene is proposed.

Process route upstream and downstream products

Process route

3',4'-dichloro-N-methylacetoacetoanilide
105942-47-0

3',4'-dichloro-N-methylacetoacetoanilide

N-(3,4-dichlorophenyl)-N-methyl-2-diazo-3-oxobutanamide
1374448-05-1

N-(3,4-dichlorophenyl)-N-methyl-2-diazo-3-oxobutanamide

Conditions
Conditions Yield
With 4-toluenesulfonyl azide; triethylamine; In acetonitrile; at 20 ℃; Inert atmosphere;
80%
3,4-dichloro-N-methylaniline
40750-59-2

3,4-dichloro-N-methylaniline

N-(3,4-dichlorophenyl)-N-methyl-2-diazo-3-oxobutanamide
1374448-05-1

N-(3,4-dichlorophenyl)-N-methyl-2-diazo-3-oxobutanamide

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 5,5-dimethyl-1,3-cyclohexadiene / 120 - 150 °C / Inert atmosphere
2: 4-toluenesulfonyl azide; triethylamine / acetonitrile / 20 °C / Inert atmosphere
With 4-toluenesulfonyl azide; triethylamine; In 5,5-dimethyl-1,3-cyclohexadiene; acetonitrile;

Global suppliers and manufacturers

Global( 0) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1374448-05-1
Post Buying Request Now
close
Remarks: The blank with*must be completed