1374761-43-9

Basic information

• Product Name: N-isopropyl-N-(thiophen-2-ylmethyl)-2-(p-tolyloxy)acetamide
• CAS NO: 1374761-43-9
• Molecular Weight: 303.425
• Mol File: 1374761-43-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-isopropyl-N-(thiophen-2-ylmethyl)-2-(p-tolyloxy)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-isopropyl-N-(thiophen-2-ylmethyl)-2-(p-tolyloxy)acetamide(1374761-43-9)
• EPA Substance Registry System: N-isopropyl-N-(thiophen-2-ylmethyl)-2-(p-tolyloxy)acetamide(1374761-43-9)

Safety Data

• Hazardous Substances Data: 1374761-43-9(Hazardous Substances Data)

Upstream product

• 106-44-5 p-cresol 
• 940-64-7 2-(4-methylphenoxy)acetic acid 
• 259655-05-5 N-isopropyl-N-(2-thiophenylmethyl)amine 
• 15516-47-9 2-(4-methylphenoxy)acetyl chloride 

Relevant articles and documents

Discovery and development of a novel class of phenoxyacetyl amides as highly potent TRPM8 agonists for use as cooling agents

The paper presents the activity trends for a novel series of phenoxyacetyl amides as human TRPM8 receptor agonists. This series encompasses in vitro activity values ranging from the micromolar to the picomolar levels. Sensory evaluation of these molecules highlights their relevance as cooling agents for oral applications. The positive outcome of the complete evaluation of N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)-2-(p-tolyloxy)acetamide resulted in its approval for Generally Recognized As Safe (GRAS) status by the Flavor & Extract Manufacturer Association (FEMA) as FEMA 4809.