1376191-77-3

Basic information

• Product Name: C₁₇H₁₇NO
• Synonyms: C₁₇H₁₇NO
• CAS NO: 1376191-77-3
• Molecular Weight: 251.328
• Mol File: 1376191-77-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₇NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₇NO(1376191-77-3)
• EPA Substance Registry System: C₁₇H₁₇NO(1376191-77-3)

Safety Data

• Hazardous Substances Data: 1376191-77-3(Hazardous Substances Data)

Upstream product

• 1376191-72-8 (2S)-1-((1S)-1-phenyl-2-undecyn-1-yl)-α,α-diphenylprolinol 

Downstream Products

• 22348-32-9 (S)-diphenylprolinol 

Relevant articles and documents

Highly enantioselective synthesis of chiral allenes by sequential creation of stereogenic center and chirality transfer in a single pot operation

Chiral allenes are readily accessed in a single pot operation in the reaction of terminal alkynes, aldehydes, chiral secondary amines, and zinc halides in good yields (up to 77% yield) and excellent enantioselectivities (up to 99% ee) in toluene at 120 °C. The reaction proceeds through initial formation of chiral propargylamine intermediates with creation of a new stereogenic center and subsequent chirality transfer via an intramolecular hydride shift to produce chiral allenes with high enantiomeric purities.