1380438-76-5

Basic information

• Product Name: (-)-(R)-(E)-3-(4-phenylbut-3-en-2-yl)furan-2(5H)-one
• Synonyms: (-)-(R)-(E)-3-(4-phenylbut-3-en-2-yl)furan-2(5H)-one
• CAS NO: 1380438-76-5
• Molecular Weight: 214.264
• Mol File: 1380438-76-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (-)-(R)-(E)-3-(4-phenylbut-3-en-2-yl)furan-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(R)-(E)-3-(4-phenylbut-3-en-2-yl)furan-2(5H)-one(1380438-76-5)
• EPA Substance Registry System: (-)-(R)-(E)-3-(4-phenylbut-3-en-2-yl)furan-2(5H)-one(1380438-76-5)

Safety Data

• Hazardous Substances Data: 1380438-76-5(Hazardous Substances Data)

Upstream product

• 36004-04-3 ethyl (E)-1-phenylbut-1-en-3-ol 
• 61550-02-5 (furan-2-yloxy)-trimethylsilane 
• 307318-11-2 methyl [(E)-1-methyl-3-phenyl-2-propenyl]carbonate 
• 82045-04-3 (rac)-(E)-2-acetoxy-4-phenylbut-3-ene 

Relevant articles and documents

Highly enantioselective synthesis of 3-substituted furanones by palladium-catalyzed kinetic resolution of unsymmetrical allyl acetates

Resolving the issue: A near-perfect Pd-catalyzed kinetic resolution of 1,3-disubstituted unsymmetrical allylic acetates uses silyl enol ethers as nucleophiles to access the important 3-substituted-furanone scaffold (see scheme; DACH=diaminocyclohexyl, dba=dibenzylideneacetone). The reaction proceeds under mild conditions and provides the desired products with excellent chemo-, regio-, and enantioselectivity. Copyright