1398609-81-8

Basic information

• Product Name: Spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-carboxylic acid, 5'-acetyl-, 1,1-diMethylethyl ester
• Synonyms: Spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-carboxylic acid, 5'-acetyl-, 1,1-diMethylethyl ester;tert-butyl 5'-acetyl-3'H-spiro[azetidine-3,1'-[2]benzofuran]-1-carboxylate;tert-Butyl 5'-acetyl-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate;Spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-carboxylic acid, 5'-acetyl-, 1,1-dimethylethyl este;5-ACETYLSPIRO[AZETIDINE-3,1(3H)-ISOBENZOFURAN]-1-CARBOXYLIC ACID, 1,1-DIMETHYLETHYL ESTER
• CAS NO: 1398609-81-8
• Molecular Formula: C₁₇H₂₁NO₄
• Molecular Weight: 303.36
• Mol File: 1398609-81-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-carboxylic acid, 5'-acetyl-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-carboxylic acid, 5'-acetyl-, 1,1-diMethylethyl ester(1398609-81-8)
• EPA Substance Registry System: Spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-carboxylic acid, 5'-acetyl-, 1,1-diMethylethyl ester(1398609-81-8)

Safety Data

• Hazardous Substances Data: 1398609-81-8(Hazardous Substances Data)

Usage

General Description

Spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-carboxylic acid, 5'-acetyl-, 1,1-diMethylethyl ester is a chemical compound with a complex molecular structure. It is a derivative of the azetidine and isobenzofuran compounds, with an acetyl group and isobutyl ester. Spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-carboxylic acid, 5'-acetyl-, 1,1-diMethylethyl ester may have pharmaceutical applications, as it contains an acetyl group which is often used in pharmaceuticals for its analgesic and anti-inflammatory properties. Additionally, the isobutyl ester group can be used to enhance the solubility and bioavailability of the compound. Further research and evaluation would be needed to determine the specific uses and potential benefits of this chemical.

Upstream product

• 1398609-80-7 tert-butyl 6-bromospiro[1H-isobenzofuran-3,3‘-azetidine]-1‘-carboxylate 
• 3375-31-3 palladium diacetate 
• 398489-26-4 tert-butyl 3-oxoazetidine-1-carboxylate 
• 1261817-10-0 4-bromo-2-(chloromethyl)-1-iodobenzene 
• 111-34-2 -butyl vinyl ether 

Downstream Products

• 1398610-04-2 tert-butyl 6-[(E/Z)-3-(3,5-dichloro-4-fluoro-phenyl)-4,4,4-trifluoro-but-2-enoyl]spiro[1H-isobenzofuran-3,3'-azetidine]-1'-carboxylate 
• 1575810-72-8 4,4,4-trifluoro-1-(1-isobutyryl-3'H-spiro[azetidine-3,1'-isobenzofuran]-5'-yl)-3-(3,4,5-trichlorophenyl)but-2-en-1-one 
• 1575794-82-9 1-(5'-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-methylpropan-1-one 
• 1575810-06-8 tert-butyl 5'-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-carboxylate 
• 1575810-70-6 5'-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)-3'H-spiro[azetidine-3,1'-isobenzofuran] hydrochloride 
• 1575794-75-0 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-1-methyl-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone 
• 1575794-68-1 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydro-1H-pyrazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone 
• 1575810-65-9 3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluoro-1-(1-isobutyryl-3'H-spiro[azetidine-3,1'-isobenzofuran]-5'-yl)but-2-en-1-one 
• 1575810-62-6 3-(3,5-dichloro-4-fluorophenyl)-4,4,4-trifluoro-1-(1-(2-(methylsulfonyl)acetyl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-5'-yl)but-2-en-1-one 
• 1575794-32-9 1-(5'-(3-(3,5-dichloro-4-fluorophenyl)-3-(trifluoromethyl)-3,4-dihydro-2H-pyrrol-5-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-methylpropan-1-one 

Relevant articles and documents

ANTIPARASITIC COMPOUNDS

The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.

CRYSTALLINE FORMS OF 1-(5'-(5-(3,5-DICHLORO-4-FLUOROPHENYL)-5-(TRIFLUOROMETHYL)-4,5-DIHYDROISOXAZOL-3-YL)-3'H-SPIRO[AZETIDINE-3,1'-ISOBENZOFURAN]-1-YL)-2-(METHYLSULFONYL)ETHANONE

The present invention relates to novel crystalline modifications of 1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone. The present invention also describes compositions and methods of treating a parasitic infection or infestation in an animal in need thereof. The present invention also relates to processes for making the crystalline forms.

SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS

The invention recites spirocyclic isoxazoline derivatives of Formula (V.1), Formula (V.2), Formula (V.1.1), and Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, processes for making, and their use as a parasi