1400420-80-5Relevant articles and documents
Triazolbenzo[d]thiazoles: Efficient synthesis and biological evaluation as neuroprotective agents
Avila, Belem,Roth, Aaron,Streets, Heather,Kurth, Mark J.,Dwyer, Donard S.
, p. 5976 - 5978,3 (2020/08/31)
A number of (1H-1,2,3-triazol-1-yl)benzo[d]thiazoles were synthesized utilizing a versatile Cu-catalyzed azide-alkyne click reaction (CuAAC) on tautomeric benzo[4,5]thiazolo[3,2-d]tetrazole (1) and 2-azidobenzo[d]thiazole (2) starting materials. Moreover, one of the resulting products of this investigation, triazolbenzo[d]thiazole 22, was found to possess significant neuroprotective activity in human neuroblastoma (SH-SY5Y) cells.