1400924-19-7Relevant articles and documents
Facile synthesis of colorimetric histone deacetylase substrates
Dose, Alexander,Jost, Jan Oliver,Spiess, Antje C.,Henklein, Petra,Beyermann, Michael,Schwarzer, Dirk
supporting information, p. 9525 - 9527 (2012/11/06)
Here we report a simple procedure for generating colorimetric histone deacetylase (HDAC) substrates by solid-phase peptide synthesis based on racemization-free couplings of amino acid chlorides. We demonstrate the applicability of these substrates in HDAC assays.