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CAS

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140430-54-2

FMOC-DAP(FMOC)-OH, also known as Fmoc-dap(dnp)-oh, is a yellow crystalline powder that serves as an intermediate in the synthesis of peptides. It plays a crucial role in the preparation of DOTA-containing peptides, which are used as MMP-2-activated agents for cancer imaging.

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  • (2S)-3-[(2,4-dinitrophenyl)amino]-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid

    Cas No: 140430-54-2

  • USD $ 1.9-2.9 / Gram

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  • 140430-54-2 Structure

  • Basic information

    1. Product Name: FMOC-DAP(FMOC)-OH
    2. Synonyms: L-ALANINE, N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-3-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-;FMOC-3-(FMOC-AMINO)-L-ALANINE;FMOC-N-BETA-2,4-DINITROPHENYL-L-2,3-DIAMINOPROPIONIC ACID;FMOC-(N-BETA-(2,4-DINITROPHENYL))-L-ALPHA,BETA-DIAMINOPROPIONIC ACID;FMOC-ALPHA,BETA-DIAMINOPROPIONIC ACID(DNP)-OH;FMOC-ALPHA,BETA-DIAMINOPROPIONIC ACID(FMOC)-OH;FMOC-DAP(DNP)-OH;FMOC-DAP(FMOC)-OH
    3. CAS NO:140430-54-2
    4. Molecular Formula: C24H20N4O8
    5. Molecular Weight: 492.44
    6. EINECS: N/A
    7. Product Categories: amino acids
    8. Mol File: 140430-54-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: 1.69
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: FMOC-DAP(FMOC)-OH(CAS DataBase Reference)
    10. NIST Chemistry Reference: FMOC-DAP(FMOC)-OH(140430-54-2)
    11. EPA Substance Registry System: FMOC-DAP(FMOC)-OH(140430-54-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. F: 10
    7. HazardClass: IRRITANT
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 140430-54-2(Hazardous Substances Data)

140430-54-2 Usage

Uses

Used in Pharmaceutical Industry:
FMOC-DAP(FMOC)-OH is used as an intermediate for the synthesis of DOTA-containing peptides for cancer imaging. Its application is based on its ability to contribute to the development of MMP-2-activated agents, which are essential in the early detection and monitoring of cancer progression.
Used in Cancer Imaging:
FMOC-DAP(FMOC)-OH is used as a key component in the preparation of peptides that can be activated by MMP-2, an enzyme overexpressed in various types of cancer. This activation allows for the enhancement of cancer imaging techniques, leading to improved diagnostic accuracy and better patient outcomes.

Check Digit Verification of cas no

The CAS Registry Mumber 140430-54-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,0,4,3 and 0 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 140430-54:
(8*1)+(7*4)+(6*0)+(5*4)+(4*3)+(3*0)+(2*5)+(1*4)=82
82 % 10 = 2
So 140430-54-2 is a valid CAS Registry Number.
InChI:InChI=1/C24H20N4O8/c29-23(30)21(12-25-20-10-9-14(27(32)33)11-22(20)28(34)35)26-24(31)36-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19/h1-11,19,21,25H,12-13H2,(H,26,31)(H,29,30)/t21-/m0/s1

140430-54-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name Fmoc-(N-beta-(2,4-dinitrophenyl))-L-alpha,beta-diaminopropionic acid

1.2 Other means of identification

Product number -
Other names (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-((2,4-dinitrophenyl)amino)propanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:140430-54-2 SDS

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