14045-28-4

Basic information

• Product Name: N,N-Pentamethylenepropionamide
• Synonyms: 1-Propionylpiperidine;N,N-Pentamethylenepropionamide
• CAS NO: 14045-28-4
• Molecular Formula: C₈H₁₅NO
• Molecular Weight: 141.2108
• Mol File: 14045-28-4.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 249°Cat760mmHg
• Flash Point: 105°C
• Appearance: /
• Density: 0.972g/cm³
• Vapor Pressure: 0.0235mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: N,N-Pentamethylenepropionamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Pentamethylenepropionamide(14045-28-4)
• EPA Substance Registry System: N,N-Pentamethylenepropionamide(14045-28-4)

Safety Data

• Hazardous Substances Data: 14045-28-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H15NO/c1-2-8(10)9-6-4-3-5-7-9/h2-7H2,1H3

Upstream product

• 110-89-4 piperidine 
• 105-37-3 Ethyl propionate 
• 4799-68-2 3-benzyloxypropan-1-ol 
• 27384-95-8 1-((Z)-1-ethyl-propenyl)-piperidine 
• 98290-53-0 (4R,5S)-3-propanoyl-4-methyl-5-phenyl-1,3-oxazolidine-2-thione 
• 104499-15-2 (4S)-3-benzoyl-4-ethyl-1,3-oxazolidine-2-thione 
• 135676-69-6 1,5-Dipropionyl-[1,3,5]triazinane-2,4-dione 
• 79-03-8 propionyl chloride 
• 802294-64-0 propionic acid 
• 74-85-1 ethene 
• 201230-82-2 carbon monoxide 

Downstream Products

• 31576-78-0 6-chloro-3-methyl-4-phenyl-2-(1-piperidyl)quinoline 
• 25991-45-1 1-(1-methylpropyl)piperidine 
• 89617-49-2 N-((S)-α-Phenylethyl)-3(S)-methyl-4(R)-trans-phenylazetidin-2-one 
• 89617-51-6 N-((S)-α-Phenylethyl)-3(R)-methyl-4(R)-cis-phenylazetidin-2-one 
• 89617-50-5 N-((S)-α-Phenylethyl)-3(S)-methyl-4(S)-cis-phenylazetidin-2-one 
• 89578-33-6 N-((S)-α-Phenylethyl)-3(R)-methyl-4(S)-trans-phenylazetidin-2-one 
• 24956-53-4 1-(2-benzoylpropanoyl)piperidine 
• 5309-95-5 1-(piperidin-1-yl)propane-1-thione 
• 116596-04-4 threo-N-(3-hydroxy-3-phenyl-2-methylpropanoyl)piperidine 
• 116836-46-5 erythro-N-(3-hydroxy-2-methyl-3-phenylpropanoyl)piperidine 
• 159097-48-0 2-(3,5-Dibromo-2-methoxyphenyl)-5-[1-(1-piperidinyl)propyl]-1H-pyrrole hydrochloride 
• 32213-47-1 threo-2-methyl-3-piperidino-1-phenylpropanol 
• 3479-86-5 1,1-dibromo-butan-2-one 
• 816-40-0 1-Bromo-2-butanone 

Relevant articles and documents

4-Phenyl quinoline derivatives as potential serotonin receptor ligands with antiproliferative activity

Antagonists of signaling receptors are often effective non-toxic therapeutic agents. Over the years, there have been evidences describing the role of serotonin or 5-hydroxytryptamine (5-HT) in development of cancer. Although there are reports on the antip

Bromination of enamines from tertiary amides using the petasis reagent: A convenient one-pot regioselective route to bromomethyl ketones

An original one-pot synthesis of bromomethyl ketones is achived using the Petasis reagent (dimethyltitanocene) as a key for enamine generation. Several amides were used to test the limits of the procedure by changing either the alkyl chain R or the amino portion of the starting materials. The enamines generated in situ were allowed to react with bromine at low temperature followed by hydrolysis to yield bromomethyl ketones in excellent yields (85 to 95%). Mechanistic details and optimum conditions for the reaction are briefly discussed. The present approach offers several advantages such as regioselectivity in enamine formation, good yields, mild reaction conditions, and ease of experimentation.

New, efficient, selective, and one-pot method for acylation of amines

Hydrazine hydrate with acetic and propionic acids was an efficient reagent for acylation of primary and secondary amines at reflux temperatures. The reported one-pot method is high-yielding, simple, mild, and inexpensive. Copyright Taylor & Francis Group, LLC.