141282-24-8

Basic information

• Product Name: 2,5,8,11,14-Pentaoxahexadecan-16-ol, 1,1,1-triphenyl-
• CAS NO: 141282-24-8
• Molecular Formula: C29H36O6
• Molecular Weight: 480.601
• Mol File: 141282-24-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2,5,8,11,14-Pentaoxahexadecan-16-ol, 1,1,1-triphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5,8,11,14-Pentaoxahexadecan-16-ol, 1,1,1-triphenyl-(141282-24-8)
• EPA Substance Registry System: 2,5,8,11,14-Pentaoxahexadecan-16-ol, 1,1,1-triphenyl-(141282-24-8)

Safety Data

• Hazardous Substances Data: 141282-24-8(Hazardous Substances Data)

Usage

Class

Triphenylmethanol (a type of organic compound containing a triphenylmethyl group)

Physical state at room temperature

White solid

Molecular weight

509.57 g/mol

Uses

Organic synthesis reactions, building block for creating other chemical compounds

Potential applications

Drug design and pharmaceutical research due to unique chemical structure and properties.

Upstream product

• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 76-83-5 trityl chloride 
• 105589-77-3 2-(2-trityloxyethoxy)ethanol 
• 27712-99-8 1,3,6,9,2λ⁴-Tetraoxathia-2-cycloundecanon 
• 4792-15-8 Pentaethylene glycol 

Downstream Products

• 675606-49-2 tert-butyldimethyl-{4-[2-(2-{2-[2-(trityloxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]phenoxy}silane 
• 1002323-05-8 C₄₀H₅₇BrO₆ 
• 635287-21-7 [2-(2-{2-[2-(2-trityloxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]acetic acid 
• 4792-15-8 Pentaethylene glycol 
• 1056881-16-3 3-O-MEM-6-O-TrO-PEG₅-nalbuphine 
• 1453169-19-1 C₃₀H₃₆O₆ 

Relevant articles and documents

Highly efficient synthesis of monodisperse poly(ethylene glycols) and derivatives through macrocyclization of oligo(ethylene glycols)

A macrocyclic sulfate (MCS)-based approach to monodisperse poly(ethylene glycols) (M-PEGs) and their monofunctionalized derivatives has been developed. Macrocyclization of oligo(ethylene glycols) (OEGs) provides MCS (up to a 62-membered macrocycle) as versatile precursors for a range of monofunctionalized M-PEGs. Through iterative nucleophilic ring-opening reactions of MCS without performing group protection and activation, a series of M-PEGs, including the unprecedented 64-mer (2850Da), can be readily prepared. Synthetic simplicity coupled with versatility of this new strategy may pave the way for broader applications of M-PEGs. Macrocycles make synthesis easier: Convenient macrocyclization of the OEGs provides versatile macrocyclic sulfates. These compounds are cornerstones for both monofunctionalization of OEGs and highly efficient synthesis of monodisperse PEGs and derivatives, including an unprecedented 64-mer.

OLIGOMER-OPIOID AGONIST CONJUGATES

The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer. -

GALACTOSE DERIVATIVE, DRUG CARRIER AND MEDICINAL COMPOSITION

The object of the invention is to provide a novel and useful galactose derivative constituting a drug carrier by which a medicine can be efficiently transferred into the liver, a drug carrier comprising the derivative, and a pharmaceutical composition comprising the carrier and a medicine. The present invention relates to a galactose derivative made up of galactose, a suitable spacer and a certain lipid, a drug carrier comprising the derivative and a cationic lipid, and a pharmaceutical composition comprising the carrier and a medicine (preferably a double strand RNA, a double strand DNA, an oligo nucleic acid) .