1416136-82-7

Basic information

• Product Name: 2-[3-(benzyloxy)phenyl]-1,1-bis(4-hydroxyphenyl)-1-butene
• Synonyms: 2-[3-(benzyloxy)phenyl]-1,1-bis(4-hydroxyphenyl)-1-butene
• CAS NO: 1416136-82-7
• Molecular Weight: 422.524
• Mol File: 1416136-82-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[3-(benzyloxy)phenyl]-1,1-bis(4-hydroxyphenyl)-1-butene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[3-(benzyloxy)phenyl]-1,1-bis(4-hydroxyphenyl)-1-butene(1416136-82-7)
• EPA Substance Registry System: 2-[3-(benzyloxy)phenyl]-1,1-bis(4-hydroxyphenyl)-1-butene(1416136-82-7)

Safety Data

• Hazardous Substances Data: 1416136-82-7(Hazardous Substances Data)

Upstream product

• 37951-47-6 3-benzyloxyphenyl ethyl ketone 
• 611-99-4 4,4'-Dihydroxybenzophenone 
• 62932-75-6 <3-(benzyloxy)phenyl>acetone 

Downstream Products

• 1416136-84-9 2-(3-hydroxyphenyl)-1,1-bis{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1-butene 
• 1416136-85-0 2-[3-(N-biotinyl-6-aminohexanoyl)phenyl]-1,1-bis{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1-butene 
• 1416136-87-2 2-(3-hydroxyphenyl)-1,1-bis{4-[2-(morpholin-4-yl)ethoxy]phenyl}-1-butene 
• 1416136-88-3 2-[3-(N-biotinyl-6-aminohexanoyl)phenyl]-1,1-bis{4-[2-(morpholin-4-yl)ethoxy]phenyl}-1-butene 
• 1416136-83-8 2-[3-(benzyloxy)phenyl]-1,1-bis{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-1-butene 
• 1416136-86-1 2-[3-(benzyloxy)phenyl]-1,1-bis{4-[2-(morpholin-4-yl)ethoxy]phenyl}-1-butene 

Relevant articles and documents

Ridaifen B, a tamoxifen derivative, directly binds to Grb10 interacting GYF protein 2

Ridaifen B (RID-B) is a tamoxifen derivative that potently inhibits breast tumor growth. RID-B was reported to show anti-proliferating activity for a variety of estrogen receptor (ER)-positive human cancer cells. Interestingly, RID-B was also reported to possess higher potency than that of tamoxifen even for some ER-negative cells, suggesting an ER-independent mechanism of action. In this study, a T7 phage display screen and subsequent binding analyses have identified Grb10 interacting GYF protein 2 (GIGYF2) as a RID-B-binding protein. Using a cell-based assay, the Akt phosphorylation level mediated by GIGYF2 was found to have decreased in the presence of RID-B.