141694-95-3

Basic information

• Product Name: S-1-trimethylsilyl-5-trimethylsilyloxymethyl-2-pyrrolidinone
• Synonyms: S-1-trimethylsilyl-5-trimethylsilyloxymethyl-2-pyrrolidinone
• CAS NO: 141694-95-3
• Molecular Weight: 259.496
• Mol File: 141694-95-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: S-1-trimethylsilyl-5-trimethylsilyloxymethyl-2-pyrrolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: S-1-trimethylsilyl-5-trimethylsilyloxymethyl-2-pyrrolidinone(141694-95-3)
• EPA Substance Registry System: S-1-trimethylsilyl-5-trimethylsilyloxymethyl-2-pyrrolidinone(141694-95-3)

Safety Data

• Hazardous Substances Data: 141694-95-3(Hazardous Substances Data)

Upstream product

• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 17342-08-4 (S)-Pyroglutaminol 

Relevant articles and documents

Synthesis of chiral pyrrolidine derivatives from (S)-pyroglutamic acid. I: 7-Substituted (2R,5S)-2-aryl-1-aza-3-oxabicyclo[3.3.0]octan-8-ones, 7- substituted (2R,5S)-2-aryl-1-aza-3-oxabicyclo[3.3.0]oct-6-en-8-ones and 3- substituted (S)-5-(hydroxymethyl)-2-pyrrolidinones

The following chiral pyrrolidine derivatives, 7-substituted (2R,5S)-2- aryl-1-aza-3-oxabicyclo[3.3.0]octan-8-ones (18-24), 7-substituted (2R,5S)-2- aryl-1-aza-3-oxabicyclo[3.3.0]oct-6-en-8-ones (25-29) and 3-substituted (S)- 5-(hydroxymethyl)-2-pyrrolidinones (30-34), were synthesized starting from (S)-pyroglutamic acid and their absolute configurations were determined based on their 1H-NMR spectra.