141719-86-0Relevant articles and documents
Photoregulation of Gene Expression with Amantadine-Modified Caged siRNAs through Host–Guest Interactions
Zhang, Jinhao,Jing, Nannan,Fan, Xinli,Tang, Xinjing
, p. 14002 - 14010 (2020)
RNA interference is an essential and powerful tool for targeting and verifying specific gene functions. Conditional control of small interfering RNA (siRNA) activity, especially using light activation, is a potential method for regulating target gene expr
A photoactivatable microRNA probe for identification of microRNA targets and light-controlled suppression of microRNA target expression
Chen, Lei,Li, Jinbo,Sun, Yu.,Zhang, Yan
, p. 627 - 630 (2020)
Here, we report a novel dual-functional microRNA (miRNA) probe, PA-miRNA, for miRNA target identification and light control of miRNA target expression. PA-miRNA is a miRNA mimic with a 3′-biotin tag linked via a photo-cleavable linker. Using PA-miR-34a, i
A photolabile linker for reversible introduction of ligands into oligonucleotides
Abramova,Bugreev,Dobrikov,Leonetti,Lebleu
, p. 172 - 178 (2007/10/03)
A photolabile linker, 1-(o-nitrophenyl)-2-aminoethanol, was synthesized for the reversible introduction of various groups into synthetic oligonucleotides. With this reagent, phenazinium and biotin dodecanucleotide derivatives were prepared. The biotin dod
