1421-89-2

Basic information

• Product Name: 2-Dimethylaminoethyl acetate
• Synonyms: 2-DIMETHYLAMINOETHYL ACETATE;ACETIC ACID 2-(DIMETHYLAMINO)ETHYL ESTER;2-DIMETHYLAMINOETHYL ACETATE 98%;2-(N,N-Dimethylamino)-1-acetyloxyethane;2-(N,N-Dimethylamino)ethyl acetate;2-Dimethylaminoethyl acetate,98%;2-dimethylaminoethanolacetate;dimethylaminoethanolacetate
• CAS NO: 1421-89-2
• Molecular Formula: C₆H₁₃NO₂
• Molecular Weight: 131.17
• EINECS: 215-827-4
• Mol File: 1421-89-2.mol
• Article Data: 8

Chemical Properties

• Melting Point: 129-130 °C
• Boiling Point: 152-154 °C
• Flash Point: 47 °C
• Appearance: Clear light yellow/Liquid
• Density: 0.92
• Vapor Pressure: 3.15mmHg at 25°C
• Refractive Index: 1.4155-1.4175
• Storage Temp.: Flammables area
• PKA: 8.56±0.28(Predicted)
• CAS DataBase Reference: 2-Dimethylaminoethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Dimethylaminoethyl acetate(1421-89-2)
• EPA Substance Registry System: 2-Dimethylaminoethyl acetate(1421-89-2)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-21/22-10
• Safety Statements: 36/37/39-26-16
• RIDADR: 1993
• RTECS: AH2100000
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 1421-89-2(Hazardous Substances Data)

Usage

Chemical Properties

clear light yellow liquid

InChI:InChI=1/C6H13NO2/c1-6(8)9-5-4-7(2)3/h4-5H2,1-3H3/p+1

Upstream product

• 108-01-0 2-(N,N-dimethylamino)ethanol 
• 75-36-5 acetyl chloride 
• 1529-79-9 Tris-<2-dimethylamino-ethyl>-arsenit 
• 108-24-7 acetic anhydride 
• 927-68-4 bromoethyl acetate 
• 124-40-3 dimethyl amine 
• 830-03-5 4-nitrophenol acetate 
• 23950-06-3 (-)-α-codeimethine 
• 107-99-3 2-(dimethylamino)ethyl chloride 
• 71-43-2 benzene 
• 1391906-41-4 2-(dimethylamino)ethyl ethyl carbonate 
• 127-08-2 potassium acetate 
• 64-19-7 acetic acid 
• 88878-78-8 tyrosine tert-butyl ester 

Downstream Products

• 22056-67-3 benzenesulfonic acid ; (2-acetoxy-ethyl)-trimethyl-ammonium salt 
• 38697-55-1 (2-acetoxy-ethyl)-(2-benzhydryloxy-ethyl)-dimethyl-ammonium; bromide 
• 38697-58-4 (2-Acetoxy-ethyl)-(3-hydroxy-3,3-diphenyl-propyl)-dimethyl-ammonium; bromide 
• 121-44-8 triethylamine 
• 51-84-3 acetylcholine 
• 74-88-4 methyl iodide 
• 1025957-53-2 C₂₁H₃₃Cl₄N₄O₅P 
• 108-01-0 2-(N,N-dimethylamino)ethanol 
• 64-19-7 acetic acid 
• 155955-36-5 2-(N,N-dimethylamino)ethyl 3-hydroxy-3-(4-nitrophenyl)propionate 
• 24000-91-7 (2-Acetoxy-ethyl)-dimethyl-(3-oxo-3-phenyl-propyl)-ammonium; iodide 

Relevant articles and documents

Amine oxide analogs of certain cholinergic agents.

-

Sulfur and nitrogen mustard carbonate analogues

Sulfur and nitrogen half-mustard compounds lose their aggressive properties when the chlorine atom is replaced by a carbonate moiety. The anchimeric effect of the novel mustard carbonate analogues is investigated. The reaction follows first-order kinetics, does not need any base, and occurs with -OH, -NH and acidic -CH nucleophiles. Most of these molecules are unexplored and might provide a novel strategy for the preparation of compounds previously not easily accessible. Copyright

Synthesis and characterization of photolabile compounds releasing noracetylcholine in the microsecond time range

The rapid and efficient photochemical release of noracetylcholine 2, an analogue of the neurotransmitter acetylcholine, from its precursor 1 makes this probe well-suited for a dynamic study of the mechanism of hydrolysis of acetylcholine by acetylcholinesterase. The nitrobenzyl derivative 1, the most promising candidate for time-resolved crystallographic studies of this rapid enzyme, displays the required photo-fragmentation kinetics in the microsecond time-range and inhibitory properties oacetylcholinesterase.