1421270-75-8

Basic information

• Product Name: 4-(benzyloxy)-1-(hydroxymethyl)cyclohexanecarbonitrile
• Synonyms: 4-(benzyloxy)-1-(hydroxymethyl)cyclohexanecarbonitrile
• CAS NO: 1421270-75-8
• Molecular Weight: 245.321
• Mol File: 1421270-75-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(benzyloxy)-1-(hydroxymethyl)cyclohexanecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(benzyloxy)-1-(hydroxymethyl)cyclohexanecarbonitrile(1421270-75-8)
• EPA Substance Registry System: 4-(benzyloxy)-1-(hydroxymethyl)cyclohexanecarbonitrile(1421270-75-8)

Safety Data

• Hazardous Substances Data: 1421270-75-8(Hazardous Substances Data)

Upstream product

• 1421270-74-7 ethyl 4-(benzyloxy)-1-cyanocyclohexanecarboxylate 
• 95233-32-2 4-(benzyloxy)cyclohexanecarbonitrile 
• 66500-40-1 4-(benzyloxy)cyclohexanecarboxylic acid 

Downstream Products

• 1421270-77-0 tert-butyl 7-(benzyloxy)-2-azaspiro[3.5]nonane-2-carboxylate 
• 1363383-18-9 7-hydroxy-2-azaspiro[3.5]nonane-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

SPIROCYCLIC MOLECULES AS PROTEIN KINASE INHIBITORS

The present invention relates to spirocyclic compounds of formula I, namely spirocyclic (1H-pyrazol-4-yl)-3-(1-(2,6-dichloro-3-fiuorophenyl) ethoxy)pyridin-2-amines having protein kinase inhibitory activity, and methods of synthesizing and using such compounds. Preferred compounds are c-Met and/or ALK inhibitors useful for the treatment of abnormal cell growth, such as cancers