1421689-05-5

Basic information

• Product Name: C₂₂H₂₆N₂O₄
• CAS NO: 1421689-05-5
• Molecular Weight: 382.459
• Mol File: 1421689-05-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₆N₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₆N₂O₄(1421689-05-5)
• EPA Substance Registry System: C₂₂H₂₆N₂O₄(1421689-05-5)

Safety Data

• Hazardous Substances Data: 1421689-05-5(Hazardous Substances Data)

Upstream product

• 1421689-03-3 C₁₇H₁₉NO₃ 
• 149505-94-2 tert-butyl (4-hydroxybenzyl)carbamate 
• 2882-19-1 ethyl 2-phenyl-2-bromoacetate 

Downstream Products

• 1421688-94-9 ethyl 2-(4-(((S)-1-((S)-2-amino-3-phenylpropanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 
• 1421688-95-0 ethyl 2-(4-((S)-1-((S)-2-amino-3-(4-methoxyphenyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 
• 1421688-96-1 ethyl 2-(4-(((S)-1-((S)-2-amino-3-(4-cyanophenyl)propanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 
• 1421688-97-2 ethyl 2-(4-(((S)-1-((S)-2-amino-3-(4-(trfluoromethyl)phenyl)propanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 
• 1421688-98-3 ethyl 2-(4-(((S)-1-((S)-2-amino-3-(4-fluorophenyl)propanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 
• 1421688-99-4 ethyl 2-(4-(((S)-1-((S)-2-amino-3-(2-cyanophenyl)propanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 
• 1421689-00-0 ethyl 2-(4-(((S)-1-((S)-2-amino-3-(2-(trfluoromethyl)phenyl)propanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 
• 1421689-01-1 ethyl 2-(4-(((S)-1-((S)-2-amino-3-(3-cyanophenyl)propanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 
• 1421689-02-2 ethyl 2-(4-(((S)-1-((S)-2-amino-3-(3-(trfluoromethyl)phenyl)propanoyl)pyrrolidine-2-carboxamido)methyl)phenoxy)-2-phenylacetate 

Relevant articles and documents

Discovering Novel α-aminoacyl-Containing Proline Derivatives with Potent and Selective Inhibitory Activity Against Dipeptidyl Peptidase IV: Design, Synthesis, Biological Evaluation, and Molecular Modeling

On the basis of the enzyme-binding features of known potent inhibitors of dipeptidyl peptidase IV, novel α-aminoacyl-containing proline analogs (8Aa-8Ak, 8Ba-8Bj, 8Ca-8Ck, and 8Da-8Di) with the S configuration were designed, synthesized, and their activit