1423567-80-9

Basic information

• Product Name: C₁₈H₁₆F₄O₃
• CAS NO: 1423567-80-9
• Molecular Weight: 356.317
• Mol File: 1423567-80-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₆F₄O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₆F₄O₃(1423567-80-9)
• EPA Substance Registry System: C₁₈H₁₆F₄O₃(1423567-80-9)

Safety Data

• Hazardous Substances Data: 1423567-80-9(Hazardous Substances Data)

Upstream product

• 39637-99-5 (S)-(+)-2-methoxy-2-trifluoromethyl-2-phenylacetyl chloride 
• 403-41-8 (R)-1-(4-fluorophenyl)ethan-1-ol 

Relevant articles and documents

5-Carboxymethyl-2-(4-methylthiophenyl)-1,3,2-dioxaborolan-4-one: Synthesis, characterization and application in enantioselective reduction of ketones

The reaction of arylboronic acids with L-O-benzoyl-tartaric acid and D,L-malic acid has been studied. The obtained (acyloxy)boranes are moderately stable in solution and decompose to give boroxines. 5-Carboxymethyl-2-(4- methylthiophenyl)-1,3,2-dioxaborolan-4-one was obtained in the reaction of 4-methylthiophenylboronic acid with D,L-malic acid and characterized by X-ray structural analysis. The use of L-(-)-malic acid afforded the optically pure product which can be used as the powerful chiral reagent in the enantioselective reduction of ketones.