1425-63-4 Usage
General Description
2,4-Diamino-6,7-dimethylpteridine is a chemical compound that belongs to the class of pteridines, which are heterocyclic compounds containing a pyrimidine ring fused to an imidazole ring. It is a white crystalline powder that is slightly soluble in water and has a melting point of around 300°C. 2,4-DIAMINO-6,7-DIMETHYLPTERIDINE has various pharmaceutical applications, including as an intermediate in the synthesis of folic acid and its derivatives. It is also used in the production of several antineoplastic agents and is being investigated for its potential as an anticancer agent. Additionally, it has been studied for its role in various biological processes, including its potential as a fluorescent probe for detecting oxidative stress in cells.
Check Digit Verification of cas no
The CAS Registry Mumber 1425-63-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,2 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1425-63:
(6*1)+(5*4)+(4*2)+(3*5)+(2*6)+(1*3)=64
64 % 10 = 4
So 1425-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N6/c1-3-4(2)12-7-5(11-3)6(9)13-8(10)14-7/h1-2H3,(H4,9,10,12,13,14)
1425-63-4Relevant articles and documents
A prototype solid phase synthesis of pteridines and related heterocyclic compounds
Gibson, Colin L.,La Rosa, Salvatore,Suckling, Colin J.
, p. 1909 - 1918 (2007/10/03)
The development of a versatile solid phase synthesis of bicyclic polyaza heterocycles including pteridines, purines, and deazapurines is described. The strategy comprises the linking of a pre-formed pyrimidine through a thioether at the 2 or 4 position to a polystyrene resin, the cyclisation of the second ring, and the direct or oxidative cleavage of the product from the resin by nucleophilic substitution. This provides not only for substituent variation in the second ring, but also for variation at the site of cleavage. Limitations in the scope of the methodology are set by the intrinsic reactivity of pyrimidinyl 2- or 4-thioethers which, whilst undergoing ready nitration at C5, are surprisingly difficult to alkylate and acylate.
FORMATION OF SUBSTITUTED PTERIDINES FROM 5,6-DIAMINOPYRIMIDINES AND N-(ARYLSULFONYL)IMIDAZOLIN-2-ONES
Zav'yalov, S. I.,Zavozin, A. G.
, p. 1355 - 1357 (2007/10/02)
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