1427-12-9

Basic information

• Product Name: α-difluoromethyldiphenyl acetonitrile
• Synonyms: α-difluoromethyldiphenyl acetonitrile
• CAS NO: 1427-12-9
• Molecular Weight: 243.256
• Mol File: 1427-12-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: α-difluoromethyldiphenyl acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: α-difluoromethyldiphenyl acetonitrile(1427-12-9)
• EPA Substance Registry System: α-difluoromethyldiphenyl acetonitrile(1427-12-9)

Safety Data

• Hazardous Substances Data: 1427-12-9(Hazardous Substances Data)

Upstream product

• 75-45-6 Chlorodifluoromethane 
• 86-29-3 Diphenylacetonitrile 
• 75-46-7 trifluoromethan 
• 81290-20-2 (trifluoromethyl)trimethylsilane 

Downstream Products

• 891-89-4 α-Difluormethyl-diphenylessigsaeure 

Relevant articles and documents

α-Difluoromethylation on sp3 Carbon of Nitriles Using Fluoroform and Ruppert-Prakash Reagent

Difluoromethylation on sp3 carbon of various nitrile compounds with lithium base and fluoroform (CF3H), which is an ideal difluoromethylating reagent, is shown to provide the α-difluoromethylated nitrile products with an all-carbon q

Difluoromethylation of some C-H acids with chlorodifluoromethane under conditions of phase transfer catalysis (PTC)

Selected C-H acids react with difluorocarbene generated from chlorodifluoromethane with concentrated aqueous solution of sodium hydroxide, and a catalyst, benzyltriethylammonium chloride (TEBAC) in benzene or THF affording C-difluoromethyl substituted der