144300-56-1Relevant articles and documents
An Efficient Synthesis of (22E,25R)-1α,25,26-Trihydroxy-Δ22-Vitamin D3
Okabe, Masami,Sun, Ruen-Chu
, p. 6533 - 6536 (1993)
The title compound 2 was prepared from C22-aldehyde 3 in 51 percent overall yield.The key feature of this synthesis is a one-pot construction of the requisite side chain using α-lithiomethylenetriphenylphosphorane 4 and commercially available (S)-2-methylglycidol.
Process for the preparation of 1α,25,26-trihydroxy-22-ene-cholecalciferol
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, (2008/06/13)
A process for preparing 1α,25(R),26-trihydroxy-22E-ene-cholecalciferol and 1α,25(S),26-trihydroxy-22E-ene-cholecalciferol.