144375-66-6

Basic information

• Product Name: 4-Methoxy-1-[(1S,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-3-triisopropylsilanyl-pyridinium; chloride
• Synonyms: 4-Methoxy-1-[(1S,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-3-triisopropylsilanyl-pyridinium; chloride
• CAS NO: 144375-66-6
• Molecular Weight: 560.292
• Mol File: 144375-66-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-Methoxy-1-[(1S,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-3-triisopropylsilanyl-pyridinium; chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxy-1-[(1S,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-3-triisopropylsilanyl-pyridinium; chloride(144375-66-6)
• EPA Substance Registry System: 4-Methoxy-1-[(1S,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-3-triisopropylsilanyl-pyridinium; chloride(144375-66-6)

Safety Data

• Hazardous Substances Data: 144375-66-6(Hazardous Substances Data)

Upstream product

• 126378-42-5 4-methoxy-3-(trisopropylsilyl)pyridine 
• 161693-64-7 (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl chloroformate 
• 126378-43-6 (1R,2S,5R)-(-)-8-phenylmenthyl chloroformate 
• 126378-43-6 (-)-8-phenylmenthol chloroformate 

Downstream Products

• 154467-62-6 (R)-4-Oxo-2-pent-4-enyl-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 126378-62-9 (R)-2-(4-Methoxy-phenyl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1S,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 126378-62-9 (S)-2-(4-Methoxy-phenyl)-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1S,2R,5S)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 57707-91-2 8-phenylmenthol 
• 137769-46-1 (S)-4-Hydroxy-2-p-tolyl-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 137769-45-0 (S)-4-Oxo-2-p-tolyl-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 137769-51-8 (S)-2-Cyclohexyl-4-oxo-3,4-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 137769-48-3 (S)-2-p-Tolyl-2H-pyridine-1-carboxylic acid benzyl ester 
• 137769-49-4 (R)-2-Cyclohexyl-2H-pyridine-1-carboxylic acid benzyl ester 
• 157300-32-8 2(S)-cyclohexyl-2,3-dihydro-4-pyridone 
• 144409-60-9 (4S,9aR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2-one 
• 1001338-53-9 (4R,9aR)-4-(3,4-dimethoxyphenyl)octahydro-2H-quinolizin-2one 
• 68622-78-6 (+)-subcosine I 
• 68622-77-5 (-)-Lasubine I 

Relevant articles and documents

Synthesis and reactions of enantiopure 1-acyl-2-[triaryl(alkyl)silyl]-2,3-dihydro-4-pyridones

The addition of triphenylsilyl- or dimethylphenylsilymagnesium bromide to certain chiral 1-acylpyridinium salts affords C-2 silylated dihydro-4-pyridones in good yield and high diastereoselectivity (84 - 96% de). Reduction and substitution reactions of th

Conversion of N-Acyl-2,3-dihydro-4-pyridones to 4-Chloro-1,2-dihydropyridines Using the Vilsmeier Reagent. Synthesis of (-)-Coniine and (+/-)-Lupinine

The full details are given of a study on the conversion of dihydropyridones of the type 3 to 4-chloro-1,2-dihydropyridines 4 using a Vilsmeier reagent.The use of 1 equiv of Vilsmeier reagent under mild conditions (ClCHCCl2, rt) transformed several racemic

An efficient asymmetric synthesis of 1-acyl-2-alky-1,2-dihydropyridines

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