14446-67-4Relevant articles and documents
Hydrosilylation of nitrogen-containing organic compounds: Model studies
Chechelska-Noworyta, Aleksandra,Owińska,Hasik, Magdalena
, (2019)
1,1,3,3-tetramethyldisiloxane (M2H) was used as the hydrosilylating agent for nitrogen-containing alkene derivatives: N-allylaniline (Naa), N-allylcyclohexylamine (Nach), N-allylpiperidine (Nap), 4-vinylpyridine (4VP) and 2-vinylpyri
Nucleophilic substitution reaction of α-siloxyamines with organometallics: A new method for α-substitution of tertiary amines via their N-oxides
Tokitoh,Okazaki
, p. 4677 - 4680 (1984)
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Solvent interactions in the allylation of piperidine
Devender,Manikyamba
, p. 421 - 425 (2009)
The reaction between allylbromide and piperidine has been studied in different protic and aprotic solvents. The reaction is first order with respect to [allylbromide] and [piperidine]. A correlation analysis of the rate data with solvent properties shows that polarity (Y ), polarizability (P), and electrophilicity (E) of the solvent simultaneously influence the rate of reaction. From the regression analysis, information regarding the relative solvation of the reactants and the activated complex is obtained and a solvation model is proposed.
Photochemical Activation of Tertiary Amines for Applications in Studying Cell Physiology
Asad, Naeem,Deodato, Davide,Lan, Xin,Widegren, Magnus B.,Phillips, David Lee,Du, Lili,Dore, Timothy M.
supporting information, p. 12591 - 12600 (2017/09/23)
Representative tertiary amines were linked to the 8-cyano-7-hydroxyquinolinyl (CyHQ) photoremovable protecting group (PPG) to create photoactivatable forms suitable for use in studying cell physiology. The photoactivation of tamoxifen and 4-hydroxytamoxifen, which can be used to activate Cre recombinase and CRISPR-Cas9 gene editing, demonstrated that highly efficient release of bioactive molecules could be achieved through one- and two-photon excitation (1PE and 2PE). CyHQ-protected anilines underwent a photoaza-Claisen rearrangement instead of releasing amines. Time-resolved spectroscopic studies revealed that photorelease of the tertiary amines was extremely fast, occurring from a singlet excited state of CyHQ on the 70 ps time scale.
Tsuji-trost N-allylation with allylic acetates by using a cellulose-palladium catalyst
Vaddula, Buchi Reddy,Saha, Amit,Varma, Rajender S.,Leazer, John
supporting information, p. 6707 - 6709 (2013/01/15)
Allylic amines were synthesized by a simple procedure using a biodegradable and easily recyclable heterogeneous cellulose-Pd catalyst through N-allylation of primary and secondary amines. The scope of this protocol includes aliphatic and benzylamines with substituted and unsubstituted allyl acetates and culminates in high yield syntheses. The highlights of the protocol include a ligand-free reaction, simple workup, and catalyst recyclability. Allylic amines were synthesized by N-allylation of primary and secondary amines through a simple and easy procedure involving the use of a heterogeneous cellulose-Pd catalyst; aliphatic and benzylamines underwent facile reaction with substituted and unsubstituted allyl acetates in high yields. Copyright