1451878-43-5

Basic information

• Product Name: (Z)-2-(3-ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide
• CAS NO: 1451878-43-5
• Molecular Weight: 178.191
• Mol File: 1451878-43-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-2-(3-ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-(3-ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide(1451878-43-5)
• EPA Substance Registry System: (Z)-2-(3-ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide(1451878-43-5)

Safety Data

• Hazardous Substances Data: 1451878-43-5(Hazardous Substances Data)

Upstream product

• 635-65-4 bilirubin 
• 1451878-31-1 methyl [2-(2Z)-(3-ethenyl-4-methyl-5-oxofuran-2(5H)-ylidene)]ethanoate 
• 1451878-28-6 methyl (Z)-(3-bromo-4-methyl-5-oxofuran-2(5H)-ylidene)ethanoate 
• 635-65-4 bilirubin IXα 
• 1451878-49-1 (2Z)-(3-ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanoyl chloride 
• 59107-74-3 3-bromo-4-methyl-2,5-furandione 
• 1451878-40-2 methyl [2-(2Z)-(3-ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)]ethanoate 
• 1451878-37-7 methyl [2-(2Z)-(3-bromo-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)]ethanoate 

Downstream Products

• 329314-76-3 (E)-2-(3-ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide 

Relevant articles and documents

BOX A-type monopyrrolic heterocycles modified via the Suzuki-Miyaura cross-coupling reaction

The in vivo oxidation of heme yields bilirubin which is further degraded to the bilirubin oxidation end products (BOXes) that are biologically highly active. To study the mode of action and fate of (Z)-2-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-yli

Isolation and Identification of Intermediates of the Oxidative Bilirubin Degradation

Four endogenous products of oxidative bilirubin degradation were isolated and fully characterized. The constitutional isomers belong to the propentdyopents (PDPs). Their structures and further oxidative transformations to biologically active bilirubin oxi