1464776-39-3

Basic information

• Product Name: 1-ethoxy-4-(3,3,3-trifluoroprop-1-yn-1-yl)benzene
• Synonyms: 1-ethoxy-4-(3,3,3-trifluoroprop-1-yn-1-yl)benzene
• CAS NO: 1464776-39-3
• Molecular Weight: 214.187
• Mol File: 1464776-39-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-ethoxy-4-(3,3,3-trifluoroprop-1-yn-1-yl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethoxy-4-(3,3,3-trifluoroprop-1-yn-1-yl)benzene(1464776-39-3)
• EPA Substance Registry System: 1-ethoxy-4-(3,3,3-trifluoroprop-1-yn-1-yl)benzene(1464776-39-3)

Safety Data

• Hazardous Substances Data: 1464776-39-3(Hazardous Substances Data)

Upstream product

• 79887-14-2 4-ethoxyphenylacetylene 
• 147531-11-1 trifluoromethanesulfonic acid diphenyl(trifluoromethyl)sulfonium salt 

Relevant articles and documents

Cu-promoted oxidative trifluoromethylation of terminal alkynes with difluoromethylene phosphobetaine

Difluoromethylene phosphobetaine (Ph3P+CF 2CO2-, PDFA), a known difluorocarbene reagent, was found to be able to efficiently trifluoromethylate terminal alkynes in the presence of Cu(I) and potassium fluoride. The transformation proceeded smoothly to afford the corresponding trifluoromethylated acetylenes in moderate yields. A difluorocarbene precursor, difluoromethylene phosphobetaine (Ph 3P+CF2CO2-, PDFA) was found to be able to act as a trifluoromethylating reagent in the presence of fluoride. The oxidative trifluoromethylation of terminal alkynes with PDFA promoted by Cu(I) occurred smoothly to give the corresponding trifluoromethylated acetylenes in moderate yields. Copyright