14665-97-5

Basic information

• Product Name: 2-(3,5-Di-tert-butylphenyl)-2-propanol
• Synonyms: 2-(3,5-Di-tert-butylphenyl)-2-propanol
• CAS NO: 14665-97-5
• Molecular Weight: 248.409
• Mol File: 14665-97-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3,5-Di-tert-butylphenyl)-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-Di-tert-butylphenyl)-2-propanol(14665-97-5)
• EPA Substance Registry System: 2-(3,5-Di-tert-butylphenyl)-2-propanol(14665-97-5)

Safety Data

• Hazardous Substances Data: 14665-97-5(Hazardous Substances Data)

Upstream product

• 15181-11-0 3, 5-di-tert-butyltoluene 
• 64277-87-8 methyl 3,5-di(tert-butyl)benzoate 
• 74-88-4 methyl iodide 
• 85313-44-6 t-Bumeoc-L-Phe-OH 

Downstream Products

• 85313-45-7 t-Bumeoc-Gly-OEt 
• 14665-80-6 1,3-di-tert-butyl-5-isopropylbenzene 
• 42053-02-1 2,2-Dimethyl-4-(3,5-di-tert.-butyl)phenylpentan-4d 
• 85313-49-1 t-Bumeoc-Trp-OH 
• 85313-53-7 t-Bumeoc-Lys(N-Boc)-OH*DCHA 
• 85313-58-2 t-Bumeoc-L-Phe-D-Leu-L-Arg-L-Phe-NH₂ 
• 85313-48-0 t-Bumeoc-Ser-(t-Bu)-OH*DCHA 
• 85313-43-5 t-Bumeoc-D-Leu*DCHA 
• 85313-51-5 t-Bumeoc-Val-OH*DCHA 
• 85313-56-0 t-Bumeoc-L-Phe-D-Leu-OH 
• 85313-54-8 t-Bumeoc-L-Phe-Gly-OMe 
• 85313-44-6 t-Bumeoc-L-Phe-OH 
• 85313-46-8 t-Bumeoc-Gln 
• 85313-41-3 t-Bumeoc-Ala-OH 

Relevant articles and documents

The 1-(3,5-Di-tert-butylphenyl)-1-methylethoxycarbonyl (t-Bumeoc) Residue, a Protecting Group Cleavable under Extremely Mild Acidic Conditions

The synthesis of 1-(3,5-di-tert-butylphenyl)-1-methylethoxycarbonyl fluoride (8) and its reaction with selected amino acids as well as the 13C NMR spectroscopic characterization of t-Bumeoc derivatives are described.The new protecting group is cleavable under very mild acidic conditions.The kinetics of the cleavage is studied by high-performance liquid chromatography (HPLC).The utility of the t-Bumeoc compared to the Adpoc protecting group is demonstrated taking a derivative of the molluscan neuropeptide as an example.