146830-59-3Relevant articles and documents
Copper-Catalyzed and Indium-Mediated Methoxycarbonylation of Unactivated Alkyl Iodides with Balloon CO
Chen, Yanchi,Su, Lei,Gong, Hegui
supporting information, p. 4689 - 4693 (2019/06/27)
This work emphasizes the synthesis of alkyl esters via Cu-catalyzed and In-mediated alkoxycarbonylation of unactivated alkyl iodides in the presence of In or InI. The reactions were suitable for the preparation of primary, secondary, and even tertiary alkyl esters, representing an exceptionally rare example for the creation of quaternary carbon centers upon formation of esters. The preliminary mechanistic studies indicated that alkyl radicals were involved, and Cu/In/CO played a cooperative role in the carbonylation event.
A new method for cleavage of silicon-carbon linkers on glass plate supports with applications to solid-phase syntheses on silica resins
Terauchi, Takeshi,Machida, Sachiko,Komba, Shiro
supporting information; experimental part, p. 1497 - 1499 (2010/04/29)
We describe herein a novel and facile method for the cleavage of a silicon-based linker on solid-phase supports such as glass plates or silica resin. The linker was efficiently cleaved by oxidation of the silicon-carbon bond (Tamao-Kumada oxidation) to re
Catalytic asymmetric synthesis of macrocyclic (E)-allylic alcohols from ω-alkynals via intramolecular 1-alkenylzinc/aldehyde additions
Oppolzer,Radinov,El-Sayed
, p. 4766 - 4770 (2007/10/03)
The ω-alkynals yielded macrocyclic (S)-allylic alcohols in a one-pot reaction sequence involving alkyne monohydroboration, boron to zinc transmetalation, and ((+)-DAIB)-catalyzed enantioselective intramolecular ring closure to the aldehyde function. A general study of this macrocyclization methodology is presented with respect to ligand type, size, and nature of the formed rings.
