1473417-84-3Relevant articles and documents
A short synthesis of (+)-bakuchiol
Esumi, Tomoyuki,Yamamoto, Chihiro,Fukuyama, Yoshiyasu
, p. 1845 - 1847 (2013)
The concise enantioselective total synthesis of (+)-bakuchiol has been achieved using an asymmetric 1,4-addition to construct its all-carbon chiral quaternary center based on the induction of chirality by the (2′S)-2′-phenyloxazolidinone auxiliary, followed by a one-pot transformation under aldol reaction conditions. The synthesis was completed in four steps from (E)-geranic acid in an overall yield of 53%. Georg Thieme Verlag Stuttgart · New York.