147663-00-1

Basic information

• Product Name: 3,4-DIHYDRO-1H-ISOCHROMEN-4-AMINE HYDROCHLORIDE
• Synonyms: 3,4-dihydro-1H-2-benzopyran-4-aMine hydrochloride;4-aMinoisochroMane hcl;3,4-Dihydro-1H-isochromen-4-amine HCl;3,4-dihydro-1H-2-benzopyran-4-amine;3,4-DIHYDRO-1H-ISOCHROMEN-4-AMINE HYDROCHLORIDE;isochroman-4-amine hydrochloride;3,4-Dihydro-1H-isochromen-4-amine;4-dihydro-1H-isochroMen-4-aMine hydrochloride
• CAS NO: 147663-00-1
• Molecular Formula: C9H12ClNO
• Molecular Weight: 185.65
• Product Categories: CHIRAL CHEMICALS
• Mol File: 147663-00-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 269℃
• Flash Point: 128℃
• Appearance: /
• Density: 1.106
• Vapor Pressure: 0.000726mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 9.07±0.20(Predicted)
• CAS DataBase Reference: 3,4-DIHYDRO-1H-ISOCHROMEN-4-AMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIHYDRO-1H-ISOCHROMEN-4-AMINE HYDROCHLORIDE(147663-00-1)
• EPA Substance Registry System: 3,4-DIHYDRO-1H-ISOCHROMEN-4-AMINE HYDROCHLORIDE(147663-00-1)

Safety Data

• Hazardous Substances Data: 147663-00-1(Hazardous Substances Data)

Usage

Uses

3,4-Dihydro-1H-isochromen-4-amine is used as a reactant in the preparation of isochromanamine derivatives and analogs for use as nervous system agents.

InChI:InChI=1/C9H11NO.ClH/c10-9-6-11-5-7-3-1-2-4-8(7)9;/h1-4,9H,5-6,10H2;1H

Upstream product

• 20924-56-5 isochroman-4-one 

Relevant articles and documents

Reductive amination and resolution of isochroman-4-one

The invention discloses a method for preparation of isochroman-4-amine from isochroman-4-one through reductive amination and further dynamic resolution of isochroman-4-amine for preparation of R-isochroman-4-amine. The method provided by the invention has the advantages of simple operation, usage of easily available raw materials, good product yield, high optical purity of the products, etc.

METHODS OF TREATMENT OF AMYLOIDOSIS USING BI-CYCLIC ASPARTYL PROTEASE INHIBITORS

The invention relates to novel compounds and methods of treating diseases, disorders, and conditions associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.