14866-28-5 Usage
Uses
1-(2,4-Dichlorophenyl)-1,2-ethanediol (Isoconazole Impurity 7) is an impurity of Isoconazole (I798250), an antibacterial and antifungal agent used to treat vaginitis.
Check Digit Verification of cas no
The CAS Registry Mumber 14866-28-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,8,6 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 14866-28:
(7*1)+(6*4)+(5*8)+(4*6)+(3*6)+(2*2)+(1*8)=125
125 % 10 = 5
So 14866-28-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H8Cl2O2/c9-5-1-2-6(7(10)3-5)8(12)4-11/h1-3,8,11-12H,4H2
14866-28-5Relevant articles and documents
Ru-MACHO-Catalyzed Highly Chemoselective Hydrogenation of α-Keto Esters to 1,2-Diols or α-Hydroxy Esters
Gao, Shaochan,Tang, Weijun,Zhang, Minghui,Wang, Chao,Xiao, Jianliang
supporting information, p. 1748 - 1752 (2016/07/06)
A ruthenium pincer catalyst has been shown to be highly effective for the hydrogenation of a wide range of α-keto esters, affording either diols or hydroxy esters depending on the choice of reaction conditions. Strong base, high temperature, and pressure favor the formation of diols whilst the opposite is true for the hydroxy esters.