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FMOC-ARG(ALOC)2-OH is a specialized chemical compound utilized in the domain of biochemistry, particularly for peptide synthesis. It is composed of the 9-fluorenylmethoxycarbonyl (FMOC) group attached to the amino acid arginine, with two alloxycarbonyl (ALOC) protecting groups. FMOC-ARG(ALOC)2-OH is integral to the process of solid-phase peptide synthesis, where it serves as a crucial building block for the stepwise construction of peptide chains. The FMOC-ARG(ALOC)2-OH is highly valued for its protective role over the amine group of arginine during the synthesis process, facilitating the assembly of complex peptide structures. It is a fundamental component in the development of peptide compounds for research, pharmaceuticals, and a variety of applications within the biotechnology sector.

148893-34-9

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Basic information
1. Product Name: FMOC-ARG(ALOC)2-OH
2. Synonyms: N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N',N''-BIS-ALLYLOXYCARBONYL-L-ARGININE;FMOC-L-ARG(ALLOC)2-OH;FMOC-ARG(ALOC)2-OH;FMOC-N-OMEGA,N-OMEGA'-BIS-(ALLYLOXYCARBONYL)-L-ARGININE;N-α-Fmoc-N-ω-,N-ω′-di-allyloxycarbonyl-L-argi;(S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-5-((5,9-dioxo-4,10-dioxa-6,8-diazatrideca-1,12-dien-7-ylidene)aMino)pentanoic acid;Fmoc-L-Arg(Aloc)2-OH;N5-[Bis[[(2-propenyloxy)carbonyl]amino]methylene]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-ornithine
3. CAS NO:148893-34-9
4. Molecular Formula: C29H32N4O8
5. Molecular Weight: 564.59
6. EINECS: N/A
7. Product Categories: Amino Acids
8. Mol File: 148893-34-9.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: 1.29±0.1 g/cm3(Predicted)
6. Refractive Index: N/A
7. Storage Temp.: Store at 0-5°C
8. Solubility: N/A
9. PKA: 3.80±0.21(Predicted)
10. CAS DataBase Reference: FMOC-ARG(ALOC)2-OH(CAS DataBase Reference)
11. NIST Chemistry Reference: FMOC-ARG(ALOC)2-OH(148893-34-9)
12. EPA Substance Registry System: FMOC-ARG(ALOC)2-OH(148893-34-9)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 148893-34-9(Hazardous Substances Data)

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148893-34-9 Usage

Uses

Used in Biochemistry Research:
FMOC-ARG(ALOC)2-OH is used as a building block in solid-phase peptide synthesis for the creation of complex peptide structures. Its protective role for the amine group of arginine is essential for the successful synthesis of peptides with specific functionalities and biological activities.
Used in Pharmaceutical Development:
In the pharmaceutical industry, FMOC-ARG(ALOC)2-OH is utilized as a key component in the synthesis of peptide-based drugs. Its ability to protect the amine group during synthesis ensures the production of peptides with desired pharmacological properties, contributing to the development of novel therapeutic agents.
Used in Biotechnology Applications:
FMOC-ARG(ALOC)2-OH is employed as a fundamental component in various biotechnological applications, including the design and synthesis of bioactive peptides for use in diagnostics, therapeutics, and other bio-medical advancements. Its role in peptide synthesis is vital for the creation of innovative peptide-based products with diverse applications.

Check Digit Verification of cas no

The CAS Registry Mumber 148893-34-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,8,9 and 3 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 148893-34:
(8*1)+(7*4)+(6*8)+(5*8)+(4*9)+(3*3)+(2*3)+(1*4)=179
179 % 10 = 9
So 148893-34-9 is a valid CAS Registry Number.

148893-34-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	(2S)-5-[bis(prop-2-enoxycarbonylamino)methylideneamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid

1.2 Other means of identification

Product number	-
Other names	Fmoc-Arg(Aloc)2-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:148893-34-9 SDS

148893-34-9Upstream product

148893-34-9Downstream Products

148893-34-9Relevant academic research and scientific papers

CHROMOGENIC AND FLUOROGENIC PEPTIDE SUBSTRATES FOR THE DETECTION OF SERINE PROTEASE ACTIVITY

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Page/Page column 17; 23, (2017/02/28)

The present invention relates to chromogenic and fluorogenic substrates that can be used for the highly sensitive and selective detection of the activity of serine proteases. The present invention further relates to methods for the detection of the activi

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