151812-96-3Relevant articles and documents
Synthesis and biological evaluation of novel turn-modified gramicidin S analogues
Grotenbreg, Gijsbert M.,Spalburg, Emile,De Neeling, Albert J.,Van Der Marel, Gijsbert A.,Overkleeft, Herman S.,Van Boom, Jacques H.,Overhand, Mark
, p. 2835 - 2841 (2007/10/03)
The synthesis of novel gramicidin S analogues having additional functionalities in the turn region by employing a biomimetic approach is described. The preservation of β-sheet character in all analogues was established by NMR and the biological activity was evaluated.