1533-44-4Relevant articles and documents
Eine einfache Methode zur Herstellung von Benzoxazolen
Seha, Zdenek,Weis, Claus D
, p. 413 - 419 (2007/10/02)
The preparation of benzoxazoles by a facile one-pot reaction is reported.The reaction of carboxylic acids with 2-chloro-N-methyl-Δ1-pyrrolinium chloride in an excess of N-methyl-2-pyrrolidone afforded carboxylic acid chlorides which were converted subsequently to their 2-hydroxyanilides by addition of 2-aminophenols.Cyclization of the 2-hydroxy-anilides at elevated temperatures furnished the benzoxazoles in high yield and purity.