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15482-26-5

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15482-26-5 Usage

General Description

2-hydroxy-1-(4-methylphenyl)propan-1-one, also known as p-hydroxyacetophenone, is an organic compound with the chemical formula C9H10O2. It is a pale yellow solid with a floral, honey-like odor, commonly used as a fragrance ingredient in perfumes and personal care products. It is also known for its antioxidant properties and is used in the manufacture of pharmaceuticals and food preservatives. Additionally, 2-hydroxy-1-(4-methylphenyl)propan-1-one can be utilized as an intermediate in organic synthesis, particularly in the production of other aromatic compounds and dyes.

Check Digit Verification of cas no

The CAS Registry Mumber 15482-26-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,8 and 2 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 15482-26:
(7*1)+(6*5)+(5*4)+(4*8)+(3*2)+(2*2)+(1*6)=105
105 % 10 = 5
So 15482-26-5 is a valid CAS Registry Number.

15482-26-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-1-(4-methylphenyl)propan-1-one

1.2 Other means of identification

Product number -
Other names 2-Hydroxy-4'-methylpropiophenone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15482-26-5 SDS

15482-26-5Relevant articles and documents

An efficient method for the synthesis of α-hydroxyalkyl aryl ketones

Chen, Chengqun,Feng, Xinghua,Zhang, Guozhen,Zhao, Qin,Huang, Guosheng

, p. 3205 - 3208 (2008)

Exposure of alkyl aryl ketones to Oxone/trifluoroacetic anhydride in the presence of a catalytic amount of iodobenzene affords α-hydroxyalkyl aryl ketones in good yield. This method provides an effective and economical entry for the installation of α-hydroxy moieties into ketones and should find wide application in the construction of the α-hydroxy ketone subunit in natural product synthesis.

Organocatalytic Synthesis of Substituted Vinylene Carbonates

Onida, Killian,Haddleton, Alice J.,Norsic, Sébastien,Boisson, Christophe,D'Agosto, Franck,Duguet, Nicolas

supporting information, p. 5129 - 5137 (2021/09/18)

The organocatalytic synthesis of substituted vinylene carbonates from benzoins and acyloins was studied using diphenyl carbonate as a carbonyl source. A range of N-Heterocyclic Carbene (NHC) precursors were screened and it was found that imidazolium salts were the most active for this transformation. The reaction occurs at 90 °C under solvent-free conditions. A wide range of substituted vinylene carbonates (symmetrical and unsymmetrical, aromatic or aliphatic), including some derived from natural products, were prepared with 20–99% isolated yields (24 examples). The reaction was also developed using thermomorphic polyethylene-supported organocatalysts as recoverable and recyclable species. The use of such species facilitates the workup and allows the synthesis of vinylene carbonates on the preparative scale (>30 g after 5 runs). (Figure presented.).

Solvent-Free Synthesis of α-Amino Ketones from α-Hydroxyl Ketones via A Novel Tandem Reaction Sequence Based on Heyns Rearrangement

Li, Ling-Yu,Zeng, Qing-Le,Li, Guang-Xun,Tang, Zhuo

supporting information, p. 694 - 699 (2019/03/26)

Heyns rearrangement have been famous for carbohydrate chemists for several decades. However, this reaction was underrated as a useful method for synthetic chemists due to preparative shortcomings. Herein we developed an efficient method for the synthesis of pharmaceutically important α-amino ketones from readily available α-hydroxy ketones and secondary amines through a tandem reaction sequence based on Heyns rearrangement. The reaction smoothly proceeded by using catalytic PTSA as catalyst without solvent. Primary and secondary α-hydroxy ketones were readily used and regioselectively afforded the correspondingly α-amino ketones with moderate yield.

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