156472-71-8Relevant articles and documents
Manipulation of the C(22)-C(27) region of rapamycin: Stability issues and biological implications
Nelson, Frances C.,Stachel, Shawn J.,Eng,Sehgal, Suren N.
, p. 295 - 300 (1999)
A novel series of rapamycin derivatives with modifications in the C(22)- C(27) region has been prepared. These compounds are evaluated for their ability to prevent ring fragmentation while still retaining immunosuppressive capabilities.