156769-17-4Relevant articles and documents
A LIGNAN FROM SCHIZANDRA CHINENSIS
Ikeya, Yukinobu,Taguchi, Heihachiro,Mitsuhashi, Hiroshi,Takeda, Shigefumi,Kase, Yoshio,Aburada, Masaki
, p. 569 - 574 (1988)
A new dibenzocyclooctadiene lignan, isoschizandrin was isolated from the fruits of Schizandra chinensis.The structure was elucidated on the basis of the spectral analysis and chemical correlation with schizandrin and (+)-deoxyschizandrin.In experiments using rats, schizandrin and its derivatives, including isoschizandrin, showed inhibitory effects on stress-induced gastric ulceration (p.o).Key Word Index-Schizandra chinensis; Schizandraceae; dibenzocyclooctadiene; lignan; isoschizandrin; anti-ulcer effect.
Intramolecular Oxidative Coupling of Aromatic Compounds. VII. A Convenient Synthesis of (+/-)-Deoxyschizandrin
Carroll, Anthony R.,Read, Roger W.,Taylor, Walter C.
, p. 1579 - 1590 (2007/10/02)
A convenient synthesis of (+/-)-deoxyschizandrin was achieved through the key step of reductive coupling of the bisacetonylbiphenyl (3).The latter compound was synthesized by oxidative cleavage of the bis olefin (5) formed by Claisen rearrangement of the bismethallyl ether of 2,2',4,4'-tetramethoxybiphenyl-3,3'-diol.The synthesis of 2,2',4,4'-tetramethoxy-6,6'-di(prop-1-enyl)biphenyl-3,3'-diol (2) is also described.The diphenolic oxidation of (2) did not lead to products with β,β' carbons linked.
RUTHENIUM(IV) TETRAKIS(TRIFLUOROACETATE), A NEW OXIDIZING AGENT. II. A NEW ACCESS TO SCHIZANDRINS SKELETON USING BIARYL OXIDATIVE COUPLING OF CIS-SUBSTITUTED BUTANOLIDES
Landais, Y.,Lebrun, A.,Robin, J. P.
, p. 5377 - 5380 (2007/10/02)
The use of the title reagent -RUFTA- was applied to the first stereospecific synthesis of bridged biaryl lactones from the corresponding cis-2,3-dibenzyl- and 3-benzyl-2-benzyliden- butanolides, respectively.A short reduction sequence afforded deoxyschiza
