15686-33-6

Basic information

• Product Name: Biclotymol
• Synonyms: 6,6'-dichlor-2,2'-methylendithymol;4-chloro-2-[(5-chloro-2-hydroxy-6-methyl-3-propan-2-ylphenyl)methyl]-3-methyl-6-propan-2-ylphenol;2,2'-methylenebis(6-chlorothymole);biclotymol;Biclothymol;PHENOL, 2,2'-METHYLENEBIS[4-CHLORO-3-METHYL-6-(1-METHYLETHYL)-(BICLOTYMOL);2,2'-Methylenebis(3-methyl-4-chloro-6-isopropylphenol);2,2'-Methylenebis[4-chloro-3-methyl-6-(1-methylethyl)phenol]
• CAS NO: 15686-33-6
• Molecular Formula: C₂₁H₂₆Cl₂O₂
• Molecular Weight: 381.33594
• EINECS: 239-771-5
• Mol File: 15686-33-6.mol

Chemical Properties

• Boiling Point: 479°Cat760mmHg
• Flash Point: 243.5°C
• Appearance: /
• Density: 1.183g/cm³
• Vapor Pressure: 8.48E-10mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Biclotymol(CAS DataBase Reference)
• NIST Chemistry Reference: Biclotymol(15686-33-6)
• EPA Substance Registry System: Biclotymol(15686-33-6)

Safety Data

• Hazardous Substances Data: 15686-33-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Biclotymol is used as an active ingredient for treating conditions such as sore throat, mouth infections, and other inflammatory conditions of the throat and oral cavity. It functions by reducing the activity of enzymes involved in the inflammatory process and exhibits antimicrobial properties that inhibit the growth of bacteria and other microorganisms in the affected area.
Used in Oral Care Products:
Biclotymol is used as a therapeutic agent in oral care products to provide relief from pain and inflammation associated with oral and throat infections. Its effectiveness in combating the underlying microbial causes makes it a powerful component in maintaining oral health.

InChI:InChI=1/C21H26Cl2O2/c1-10(2)14-8-18(22)12(5)16(20(14)24)7-17-13(6)19(23)9-15(11(3)4)21(17)25/h8-11,24-25H,7H2,1-6H3

Upstream product

• 50-00-0 formaldehyd 
• 89-68-9 4-chloro-2-isopropyl-5-methylphenol 

Related news

Collective relaxation dynamics and crystallization kinetics of the amorphous Biclotymol (cas 15686-33-6) antiseptic09/01/2019

We employ dielectric spectroscopy to monitor the relaxation dynamics and crystallization kinetics of the Biclotymol antiseptic in its amorphous phase. The glass transition temperature of the material as determined by dielectric spectroscopy is Tg = 290 ± 1 K. The primary (α) relaxation dynamic...detailed

Relevant articles and documents

New aluminum 2,2′-methylenebis(4-chloro-3-methyl-6-(isopropyl) phenoxides): Structural characterization of an unusual ionic aluminum bisphenoxide [Al(THF)4(Cl)2]+[Al(mcmip) 2]-·x THF

The synthesis and X-ray structure determination of an uncommon ionic aluminum bisphenoxide [Al(THF)4(Cl)2] +[Al(mcmip)2]-·1.1 THF (1) and its neutral analogue (mcmip)Al(CH2CH3)(THF) (2) are reported (mcmipH2: 2,2′-methylenebis(4-chloro-3-methyl-6-(isopropyl) phenol). The ligand was reacted in THF with diethyl aluminum chloride, respectively triethyl aluminum, under liberation of ethane to yield crystalline aluminum bisphenoxides. Compound 2 exhibits the usual structural features found in neutral THF-aluminum bisphenoxides adducts whereas the ionic compound 1 consists of a cationic octahedral aluminum dichloride moiety, [Al(THF) 4(Cl)2], and an anionic di-bisphenoxide aluminate fragment [Al(mcmip)2] containing two 2,2′-methylenebis(4-chloro-3- methyl-6-(isopropyl)phenol) ligands. Both aluminum bisphenoxides were tested as catalysts in the copolymerization of cyclohexene oxide with CO2 and displayed similar good catalytic activities although the carbonate amounts present in the copolymer remain low.

Synthesis and structural studies of heterobimetallic alkoxide complexes supported by bis(phenolate) ligands: Efficient catalysts for ring-opening polymerization of l-lactide

A series of heteroblmetallic titanium(IV) complexes [LTi(O′Pr)(μ- O′Pr)2Li(THF)2], [LTi(O′Pr)(μ-O′Pr) 2Na(THF)2], [LTi(μ-O′Pr)2Zn(O′ Pr)2], and [LTi(μ-O′Pr)2Mg(O′Pr) 2] (where L = bidentate bisphenol ligands) have been synthesized and characterized including a structural determination of [L1Ti(μ 2-O′Pr)2(O′Pr)Li(THF)2] (1a). These complexes were investigated for their utility in the ring-opening polymerization (ROP) of L-lactide (LA). Polymerization activities have been shown to correlate with the electronic properties of the substituent within the bisphenol ligand. In contrast to monometallic titanium Initiator 1e, all the heterobimetallic titanium initiators (Ti-Li, Ti-Na, Ti-Zn, and Ti-Mg) show enhanced catalytic activity toward ring-opening polymerization (ROP) of L-LA. In addition, the use of electron-donating methoxy or methylphenylsulfonyl functional ligands reveals the highest activity. The bisphenol bimetallic complexes give rise to controlled ring-opening polymerization, as shown by the linear relationship between the percentage conversion and the number-average molecular weight. The polymerization kinetics using 2c as an initiator were also studied, and the experimental results indicate that the reaction rate is first-order with respect to both monomer and catalyst concentration with a polymerization rate constant, k = 81.64 M-1 min-1.