15781-74-5

Basic information

• Product Name: DI(2,4,6-TRICHLOROPHENYL) 2-BENZYLMALONATE
• Synonyms: AURORA KA-3281;DI(2,4,6-TRICHLOROPHENYL) 2-BENZYLMALONATE;Bis(2,4,6-trichlorophenyl) Benzylmalonate
• CAS NO: 15781-74-5
• Molecular Formula: C₂₂H₁₂Cl₆O₄
• Molecular Weight: 553.05
• Mol File: 15781-74-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 647.4°Cat760mmHg
• Flash Point: 222.3°C
• Appearance: /
• Density: 1.543g/cm³
• Vapor Pressure: 1.2E-16mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: DI(2,4,6-TRICHLOROPHENYL) 2-BENZYLMALONATE(CAS DataBase Reference)
• NIST Chemistry Reference: DI(2,4,6-TRICHLOROPHENYL) 2-BENZYLMALONATE(15781-74-5)
• EPA Substance Registry System: DI(2,4,6-TRICHLOROPHENYL) 2-BENZYLMALONATE(15781-74-5)

Safety Data

• Hazardous Substances Data: 15781-74-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H12Cl6O4/c23-12-7-15(25)19(16(26)8-12)31-21(29)14(6-11-4-2-1-3-5-11)22(30)32-20-17(27)9-13(24)10-18(20)28/h1-5,7-10,14H,6H2

Upstream product

• 607-81-8 diethyl 2-benzylmalonate 
• 100-44-7 benzyl chloride 
• 616-75-1 2-benzylmalonic acid 
• 88-06-2 2,4,6-Trichlorophenol 

Downstream Products

• 53528-87-3 6-benzyl-8-ethyl-5,7-dioxo-4,5,6,7-tetrahydro-[1,3,4]thiadiazolo[3,2-a]pyrimidinylium betaine 
• 69395-59-1 6-benzyl-2-ethylsulfanyl-[1,3,4]thiadiazolo[3,2-a]pyrimidine-5,7-dione 
• 69395-70-6 6-benzyl-2-benzylsulfanyl-[1,3,4]thiadiazolo[3,2-a]pyrimidine-5,7-dione 
• 107613-71-8 7-Benzyl-6-hydroxy-2,3-dimethyl-pyrimido[1,2-b][1,2,4]triazin-8-one 
• 13675-75-7 3-benzyl-4-hydroxy-5,6,7,8-tetrahydrochinolin-2(1H)-on 
• 107613-78-5 7-Benzyl-6-hydroxy-2,3-diphenyl-pyrimido[1,2-b][1,2,4]triazin-8-one 
• 119022-20-7 3-benzyl-4-hydroxy-7,7-dimethyl-7,8-dihydrochinolin-2,5(1H,6H)-dion 
• 97788-86-8 3-benzyl-benzo[4,5]oxazolo[3,2-a]pyrimidine-2,4-dione 
• 97684-73-6 3-Benzyl-1-methyl-4-oxo-4H-benzothiazolo<3,2-a>pyrimidin-1-ium-2-olat 
• 86796-20-5 3-Benzyl-2-hydroxy-1-propionyl-4-chinolizinon 
• 94017-99-9 5-Benzyl-6-hydroxy-2-methyl-4H-imidazo<4,5,1-ij>quinolin-4-one 
• 94018-00-5 2-Methylbenzimidazole - 2,4,6-trichlorophenol (1:1) adduct 
• 86913-31-7 1-Acetyl-3-benzyl-2-hydroxy-4-chinolizinon 
• 120537-80-6 6-amino-3-benzyl-2-hydroxy-4-oxo-4H-pyrido<1,2-a>pyrimidine 

Relevant articles and documents

Synthesis and insecticidal activity of mesoionic pyrido[1,2-α]pyrimidinone derivatives containing a neonicotinoid moiety

Mesoionic pyrido[1,2-α]pyrimidinone derivatives containing a neonicotinoid moiety were designed, synthesized, and evaluated for their insecticidal activity. Some of the title compounds showed remarkable insecticidal properties against Aphis craccivora. Compound I13 exhibited satisfactory insecticidal activity against A. craccivora. Meanwhile, label-free proteomics analysis of compound I13 treatment identified a total of 821 proteins. Of these, 35 proteins were up-regulated, whereas 108 proteins were down-regulated. Differential expressions of these proteins reflected a change in cellular structure and metabolism.

Synthesis and reactions of 4-hydroxy-8,9,10, 11-tetrahydropyrido[3,2,1-jk] carbazol-6-ones

(Chemical Equation Presented) Tetrahydrocarbazoles 4 obtained from phenylhydrazines and cyclohexanones gave by cyclocondensation with 2-substituted malonates 5 in all cases 4-hydroxy-8,9,10,11-tetrahydropyrido [3,2,1-jk]carbazol-6-ones 6 by attack at the nitrogen and the aromatic ring of tetrahydrocarbazoles 4; the direction of the cyclization was not dependent on substituents either in the aromatic or the saturated ring; isomeric pyridocarbazoles could not be isolated. Electrophilic substitutions of pyridocarbazoles 6 under mild conditions took place exclusively at the 5-position and gave pyridocarbazolediones 9-11 with 5-nitro-, 5-hydroxy or 5-chloro-substituents. Exchange of the chloro substituent in 11 gave 5-azido- and 5-amino products 12, 14 or 16. Reactions at the aromatic ring were not observed. Chlorination of 4-hydroxypyridocarbazoles 6 with phosphoryl chloride by nucleophilic substitution took place exclusively at the 4-position and gave 4-chloropyridocarbazolones 17, which were further reacted to azides and amines 18, 19.