157823-89-7

Basic information

• Product Name: [(3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-carbamic acid tert-butyl ester
• Synonyms: [(3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-carbamic acid tert-butyl ester
• CAS NO: 157823-89-7
• Molecular Weight: 469.653
• Mol File: 157823-89-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-carbamic acid tert-butyl ester(157823-89-7)
• EPA Substance Registry System: [(3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-carbamic acid tert-butyl ester(157823-89-7)

Safety Data

• Hazardous Substances Data: 157823-89-7(Hazardous Substances Data)

Upstream product

• 157823-88-6 [(3S,4R)-4-(tert-Butyl-dimethyl-silanyloxymethyl)-5-oxo-tetrahydro-furan-3-yl]-carbamic acid tert-butyl ester 
• 136703-59-8 (3S)-3-[(tert-butoxycarbonyl)amino]-4-hydroxybutanoic acid methyl ester 
• 104227-71-6 N-[(3S)-tetrahydro-5-oxo-3-furanyl]carbamic acid-1,1-dimethylethyl ester 
• 130622-08-1 dimethyl N-tert-butoxycarbonyl-L-aspartate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 157823-87-5 ((3S,4R)-4-Hydroxymethyl-5-oxo-tetrahydro-furan-3-yl)-carbamic acid tert-butyl ester 

Relevant articles and documents

Diastereoselective reactions of Grignard reagents with chiral amino lactols derived from L-aspartic acid

Nucleophilic additions to chiral amino lactols obtained from L-aspartic acid containing a chiral α-silyloxymethyl function by simple Grignard reagents exhibited high stereoselectivity to provide the corresponding optically active amino alcohols containing three contiguous stereogenic centers. The mechanistic origin of the asymmetric induction is rationalized based on chelation controlled models.