158861-67-7

Basic information

• Product Name: Pralmorelin
• Synonyms: (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide;D-Ala-bata-(2-naphthyl)-D-Ala-Trp-D-Phe-Lys amide;D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide;GHCA;D-ALANYL-3-(2-NAPHTHALENYL)-D-ALANYL-L-ALANYL-L-TRYPTOPHYL-D-PHENYLALANYL-L-LYSINAMIDE ACETATE ADDUCT;GHRP-2 (FREE PEPTIDE);D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2;4-dichloro-1
• CAS NO: 158861-67-7
• Molecular Formula: C42H50N8O5
• Molecular Weight: 746.91
• Product Categories: Peptide;Peptides
• Mol File: 158861-67-7.mol

Chemical Properties

• Boiling Point: 1186.79 °C at 760 mmHg
• Flash Point: 671.546 °C
• Appearance: /
• Density: 1.27 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.638
• Storage Temp.: −20°C
• Solubility: DMSO (Slightly, Sonicated), Water (Slightly)
• PKA: 13.40±0.46(Predicted)
• CAS DataBase Reference: Pralmorelin(CAS DataBase Reference)
• NIST Chemistry Reference: Pralmorelin(158861-67-7)
• EPA Substance Registry System: Pralmorelin(158861-67-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 158861-67-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Pralmorelin is used as a diagnostic agent for the assessment of growth hormone deficiency. It helps in identifying the appropriate treatment for patients with growth hormone-related disorders by providing a more accurate diagnosis through its ability to stimulate growth hormone release.
Used in Endocrinology:
Pralmorelin is used as a therapeutic agent for the treatment of growth hormone deficiency in children and adults. It aids in promoting growth and development by stimulating the natural production of growth hormone, which is essential for various physiological processes.
Used in Research and Development:
Pralmorelin is used as a research tool for studying the mechanisms of growth hormone secretion and its role in various physiological and pathological conditions. This helps in advancing the understanding of growth hormone regulation and the development of new therapeutic strategies for related disorders.
Used in Sports Medicine:
Pralmorelin is used as an ergogenic aid to enhance athletic performance. Its growth hormone-releasing properties can potentially improve muscle mass, strength, and recovery, making it an attractive option for athletes seeking to improve their performance. However,

Biochem/physiol Actions

Pralmorelin, also known as Growth hormone-releasing peptide 2 or GHRP-2, is an orally-active, synthetic peptide analogue of met-enkephalin that acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to selectively stimulate the ghrelin receptor and cause growth hormone release. Pralmorelin (GHRP-2) has been used clinically for the assessment of growth hormone deficiency (GHD), It has also been shown to have anti-inflammatory activity.

InChI:InChI=1/C45H55N9O6/c1-27(47)41(56)52-38(24-30-19-20-31-14-6-7-15-32(31)22-30)43(58)50-28(2)42(57)53-39(25-33-26-49-35-17-9-8-16-34(33)35)45(60)54-37(23-29-12-4-3-5-13-29)44(59)51-36(40(48)55)18-10-11-21-46/h3-9,12-17,19-20,22,26-28,36-39,49H,10-11,18,21,23-25,46-47H2,1-2H3,(H2,48,55)(H,50,58)(H,51,59)(H,52,56)(H,53,57)(H,54,60)/t27-,28+,36+,37-,38-,39+/m1/s1