159325-45-8

Basic information

• Product Name: Androstan-17-one,2,3-epoxy-16-(1-pyrrolidinyl)
• Synonyms: Androstan-17-one,2,3-epoxy-16-(1-pyrrolidinyl);2,3-epoxy-16-(1-pyrrolidinyl)-, (2α,3α,5α,16β)-;2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-one;ZZMJTNMGPPBIOY-CLGWBQSRSA-N
• CAS NO: 159325-45-8
• Molecular Formula: C₂₃H₃₅NO₂
• Molecular Weight: 357.5295
• Mol File: 159325-45-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Density: 1.18g/cm3 at 20℃
• Vapor Pressure: 0.019Pa at 20℃
• CAS DataBase Reference: Androstan-17-one,2,3-epoxy-16-(1-pyrrolidinyl)(CAS DataBase Reference)
• NIST Chemistry Reference: Androstan-17-one,2,3-epoxy-16-(1-pyrrolidinyl)(159325-45-8)
• EPA Substance Registry System: Androstan-17-one,2,3-epoxy-16-(1-pyrrolidinyl)(159325-45-8)

Safety Data

• Hazardous Substances Data: 159325-45-8(Hazardous Substances Data)

Usage

General Description

Androstan-17-one,2,3-epoxy-16-(1-pyrrolidinyl) is a chemical compound with a complex structure that includes a steroid backbone and an epoxy ring. It also contains a pyrrolidinyl group, which is a five-membered nitrogen-containing ring. Androstan-17-one,2,3-epoxy-16-(1-pyrrolidinyl) may have potential applications in the field of medicine and pharmacology due to its unique structure and functional groups. It is important to handle and use this chemical with care, as its properties and potential effects are not fully understood. Further research and studies may be necessary to fully understand the potential uses and risks associated with this compound.

Upstream product

• 123-75-1 pyrrolidine 
• 50588-22-2 2α,3α:16α,17α-diepoxy-17β-acetoxy-5α-androstane 
• 930092-99-2 2α,3α-epoxy-16α-(1-pyrrolidinyl)-5α-androstan-17-one 
• 119302-20-4 (2β,3α,5α,16β,17β)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol 
• 108-24-7 acetic anhydride 

Downstream Products

• 119302-19-1 (2α,3α,5α,16β,17β)-2,3-epoxy-16-(1-pyrrolidinyl)-androstan-17-ol 
• 144209-33-6 C₂₇H₄₆N₂O₂ 

Relevant articles and documents

Synthesis method of 16beta-tetrahydropyrrolyl androstan-2alpha-epoxy-17-one

The invention relates to the technical field of medicines and chemical industry, discloses a preparation method of an important intermediate of rocuronium bromide, namely 16beta-tetrahydropyrrolyl androstan-2alpha-epoxy-17-one. The preparation method comprises the following steps: (1), in a ball milling tank, adding 17-acetoxy androstan-2alpha,16alpha-bisepoxide, pyrrolidine and silica gel, and reacting at a certain mechanical grinding frequency; and (2), post-treating a reaction mixture, and recrystallizing to obtain the 16beta-tetrahydropyrrolyl androstan-2alpha-epoxy-17-one. The preparationmethod has the advantages of high reaction yield, short time, high selectivity, simple and convenient operation, less pollution and the like, and is an environment-friendly chemical synthesis methodwith relatively good popularization and application prospects.

Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same

There is disclosed novel, therapeutically active androstane derivatives having neuromuscular blocking effect, which are substituted by a quaternary ammonium group in 16-position; pharmaceutically composition containing them; process for producing them; and novel intermediates for the production.