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159857-61-1

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159857-61-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 159857-61-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,9,8,5 and 7 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 159857-61:
(8*1)+(7*5)+(6*9)+(5*8)+(4*5)+(3*7)+(2*6)+(1*1)=191
191 % 10 = 1
So 159857-61-1 is a valid CAS Registry Number.

159857-61-1Upstream product

159857-61-1Relevant articles and documents

Monomethoxytrityl (MMT) as a versatile amino protecting group for complex prodrugs of anticancer compounds sensitive to strong acids, bases and nucleophiles

Dubowchik, Gene M.,Radia, Shilpa

, p. 5257 - 5260 (1997)

Cathepsin B-sensitive maleimidocaproyl-Phe-Lys linker compounds containing acid-sensitive anticancer drugs doxorubicin, mitomycin C and paclitaxel (taxol) attached through a self-immolative p-aminobenzylcarbonyl spacer were prepared using monomethoxytrityl (MMT) as the amino protecting group for Lys. MMT could be removed cleanly and in high yield by dichloroacetic and chloroacetic acids in the presence of anisole with minimal workup.

Cobalamin conjugates for anti-tumor therapy

-

Page/Page column 17, (2008/06/13)

The present invention provides a cobalamin-drug conjugate suitable for the treatment of tumor related diseases. Cobalamin is indirectly covalently bound to an anti-tumor drug via a cleavable linker and one or more optional spacers. Cobalamin is covalently

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