160707-16-4

Basic information

• Product Name: (S)-4-Amino-3-(3,4-dichlorophenyl)butan-1-ol
• Synonyms: (S) (-) DICHLOROPHENYL AMINO ALCOHOL;(S)-2-(3,4-Dichlorophenyl)-4-hydroxybutylamine;(S)-4-Amino-3-(3,4-dichlorophenyl)butan-1-ol;N-[(S)-2-(3,4-Dichlorophenyl)-4-hydroxybutyl]amine;(3S)-4-amino-3-(3,4-dichlorophenyl)butan-1-ol
• CAS NO: 160707-16-4
• Molecular Formula: C₁₀H₁₃Cl₂NO
• Molecular Weight: 234.12
• Mol File: 160707-16-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 359.4°C at 760 mmHg
• Flash Point: 171.1°C
• Appearance: /
• Density: 1.292
• Vapor Pressure: 8.62E-06mmHg at 25°C
• Refractive Index: 1.576
• PKA: 14.88±0.10(Predicted)
• CAS DataBase Reference: (S)-4-Amino-3-(3,4-dichlorophenyl)butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-Amino-3-(3,4-dichlorophenyl)butan-1-ol(160707-16-4)
• EPA Substance Registry System: (S)-4-Amino-3-(3,4-dichlorophenyl)butan-1-ol(160707-16-4)

Safety Data

• Hazardous Substances Data: 160707-16-4(Hazardous Substances Data)

Usage

General Description

(S)-4-Amino-3-(3,4-dichlorophenyl)butan-1-ol, also known as "S-AMPHETAMINE," is a psychoactive drug and a potent central nervous system stimulant. It is a chiral compound, meaning it has a non-superimposable mirror image, and the (S)-enantiomer is the active form of amphetamine that is responsible for its stimulant effects. Amphetamine is commonly used for its stimulant properties and is prescribed for the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used illicitly as a recreational drug due to its euphoric effects. However, it is highly addictive and can cause a range of adverse effects including increased heart rate, elevated blood pressure, and insomnia. Amphetamine is a controlled substance in many countries due to its potential for abuse and addiction.

InChI:InChI=1/C10H13Cl2NO/c11-9-2-1-7(5-10(9)12)8(6-13)3-4-14/h1-2,5,8,14H,3-4,6,13H2/t8-/m1/s1

Downstream Products

• 255050-49-8 3-cyano-naphthalene-1-carboxylic acid [(2S)-(3,4-dichloro-phenyl)-4-hydroxy-butyl]-methyl-amide 
• 263862-54-0 3-cyano-N-[(2S)-2-(3,4-dichlorophenyl)-4-hydroxybutyl]-2-methoxy-1-naphthamide 

Relevant articles and documents

Aryl substituted heterocycles

The present invention concerns the novel use of aryl substituted heterocycles of formula I, set out below, which antagonize the pharmacological actions of one of ent endogenous neuropeptide tachykinins an the neurokinin 2 (NK2) receptor making them useful whenever such antagonism is desired, such as in the treatment of asthma and related conditions. The invention also provides pharmaceutical compositions containing the aryl substituted heterocycles for use in such treatment. Certain novel aryl substituted heterocycles of formula I and novel intermediates for their manufacture are also provided. STR1